Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
ACTN3 and KCTD6
Data Source:
BioGRID
(two hybrid)
ACTN3
KCTD6
Description
actinin alpha 3
potassium channel tetramerization domain containing 6
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Actin Filament
Focal Adhesion
Pseudopodium
Extracellular Exosome
Cytosol
M Band
Molecular Function
Actin Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Identical Protein Binding
Ion Channel Binding
Protein Binding
Ankyrin Binding
Identical Protein Binding
Cullin Family Protein Binding
Biological Process
Regulation Of The Force Of Skeletal Muscle Contraction
Skeletal Muscle Atrophy
Transition Between Fast And Slow Fiber
Response To Denervation Involved In Regulation Of Muscle Adaptation
Muscle Filament Sliding
Regulation Of Apoptotic Process
Negative Regulation Of Glycolytic Process
Focal Adhesion Assembly
Positive Regulation Of Skeletal Muscle Tissue Growth
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Oxidative Phosphorylation
Negative Regulation Of Cold-induced Thermogenesis
Regulation Of Aerobic Respiration
Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
Ubiquitin-dependent Protein Catabolic Process
Protein Ubiquitination
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Regulation Of Growth
Post-translational Protein Modification
Negative Regulation Of Smoothened Signaling Pathway
Protein Homooligomerization
Pathways
Nephrin family interactions
Striated Muscle Contraction
RUNX1 regulates estrogen receptor mediated transcription
Neddylation
Estrogen-dependent gene expression
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Frontotemporal dementia with GRN mutation (
29724592
)
Hepcidin/transferrin saturation ratio (
27846281
)
Refractive error (
32231278
)
Systemic lupus erythematosus (
28714469
)
vWF levels (
30586737
)
Interacting Genes
61 interacting genes:
ABI3
ACTN1
ACTN2
ACTN4
ADORA2A
ASB9
ATP23
BRCA1
C1orf94
C20orf85
C2CD6
CADPS
CTAG1A
CTAG1B
CTDSP1
CXCL5
DDAH2
DUX1
DUX4L9
ECM1
FAM90A1
GLIS2
HGS
HOXD12
HSF2BP
IVD
KCTD6
KRT6C
LHX3
LINC01554
LNX1
MAGEA6
MICALL2
MYOT
MYOZ1
MYPN
NDUFAB1
NEBL
NKAPD1
NRAP
ODF3B
PCCB
PKP2
PLEKHG2
POU6F2
PPP1R18
PTK6
REL
RNF111
RTP5
SNAI1
SOHLH1
SUMO1P1
SYNPO2L
TRAF1
TRAF2
TRIM29
TTN
USP2
ZNF343
ZNF426
28 interacting genes:
ACTN1
ACTN3
ANK1
BAG4
C8orf33
CDC23
CTNND1
CUL3
EHHADH
ERBB2
FAM124B
GOLGA8EP
GOLGA8F
GRB7
GSDMD
LNX1
MOS
NTAQ1
PICK1
PPIG
PRPF31
PSMA1
REL
SDCBP
TBC1D2
TCEANC
TEPSIN
ZCCHC10
Entrez ID
89
200845
HPRD ID
02148
13769
Ensembl ID
ENSG00000248746
ENSG00000168301
Uniprot IDs
A0A087WSZ2
B4DZQ2
Q08043
Q8NC69
PDB IDs
1TJT
1WKU
3LUE
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?