Description |
POU class 6 homeobox 2 |
EBF transcription factor 1 |
Image |
No pdb structure |
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Cellular Component |
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Molecular Function |
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Biological Process |
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Pathways |
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Drugs |
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Diseases |
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GWAS |
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- Adventurousness ( 30643258)
- Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
- Anorexia nervosa (excluding migration to or from binge-eating disorder or bulimia nervosa) ( 28630421)
- Apolipoprotein A1 levels ( 32203549)
- Birth weight ( 31043758 27680694)
- Blood pressure ( 21909110)
- Blood protein levels ( 29875488)
- Body size at age 10 ( 32376654)
- Breast cancer ( 29059683 23535729 23535733)
- Carotid intima media thickness ( 26343869)
- Cognitive decline rate in late mild cognitive impairment ( 26252872)
- Creatine kinase levels ( 29403010)
- Diastolic blood pressure ( 28135244 27841878 21909115 28739976 27618452)
- Diastolic blood pressure (cigarette smoking interaction) ( 29455858)
- Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098)
- General risk tolerance (MTAG) ( 30643258)
- Gestational age at birth (maternal effect) ( 28877031)
- HDL cholesterol levels ( 32203549)
- HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Heel bone mineral density ( 30598549)
- Hip circumference (psychosocial stress interaction) ( 25271088)
- Hypertension ( 21909115 30487518)
- Hypospadias ( 25108383)
- Inflammatory skin disease ( 25574825)
- Longevity (85 years and older) ( 24688116)
- Longevity (90 years and older) ( 24688116)
- Lymphocyte counts ( 32888494)
- Lymphocyte percentage of white cells ( 32888494 27863252)
- Male-pattern baldness ( 29146897 27182965 28196072)
- Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
- Mean corpuscular hemoglobin concentration ( 32888494)
- Mean platelet volume ( 32888494)
- Mean spheric corpuscular volume ( 32888494)
- Medication use (agents acting on the renin-angiotensin system) ( 31015401)
- Monocyte count ( 32888494)
- Monocyte percentage of white cells ( 32888494 27863252)
- Neutrophil percentage of white cells ( 32888494)
- Non-albumin protein levels ( 29403010)
- Obesity-related traits ( 23251661)
- Offspring birth weight ( 31043758)
- Pericardial adipose tissue adjusted for height and weight ( 27918534)
- Pericardial fat ( 27918534)
- Platelet count ( 32888494)
- Post bronchodilator FEV1 ( 26634245)
- Preterm birth (maternal effect) ( 28877031)
- Pulse pressure ( 30224653 28135244 27841878 28739976 30578418)
- Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
- Refractive error ( 32231278)
- Reticulocyte fraction of red cells ( 32888494)
- Smoking initiation (ever regular vs never regular) ( 30679032)
- Smoking status (ever vs never smokers) ( 30643258)
- Systolic blood pressure ( 26390057 28135244 27841878 21909115 28739976 27618452 30578418)
- Systolic blood pressure (cigarette smoking interaction) ( 29455858)
- Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
- Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
- Triglyceride levels ( 32203549 30698716)
- Triglyceride levels in current drinkers ( 30698716)
- Triglyceride levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
- Triglyceride levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
- Type 2 diabetes (adjusted for BMI) ( 30297969)
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Interacting Genes |
143 interacting genes:
ACTN3
ANKRD10
ARHGEF6
ASB13
BANP
BFSP2
BHLHE40
C1orf109
C5
CCHCR1
CCNC
CCNK
CDC23
CDC37
CDKN2C
CHAF1A
CIB3
CINP
CSNK2A1
CSTF2
CTNNA3
DDX6
DTNB
DYDC1
EBF1
EIF3F
EIF4EBP1
EPHB6
FHL2
FNDC3B
FOSB
GCM2
GLIS2
GMEB2
GOLGA6L9
HGS
HIVEP1
HNF1B
HOXC5
HOXC8
HSPA4
IGFN1
IMPDH2
IQUB
IRX4
ISX
KDF1
KIF5B
KLHL11
KPNA5
KPNA6
KRTAP8-1
L3MBTL2
LARP4
LMNB2
LMO3
LNX1
LONRF1
MAGEA12
MAPK9
MEIS2
MIEN1
MLLT10
MORF4L2
MSRB3
MSX2
MYL7
MYO15B
NEUROG3
NFYC
NKX3-2
NME7
NUP62CL
OAZ3
OIP5
OPLAH
OPTN
PADI4
PARVG
PDE6H
PIBF1
PKN1
PM20D2
POLR3C
POU2F1
PPIL1
PPIP5K2
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
QRICH1
RAD23B
RBM39
RBPMS
RELA
SIX1
SMAD5
SMYD1
SORL1
SOX10
SSUH2
STAC
STRA8
TBX6
TCEA2
TENT5B
THADA
THAP1
TLX2
TLX3
TNPO2
TNXB
TP53BP1
TRIM73
TRIML2
TSC1
TSEN15
TTC19
TTC23
UBAC1
UFSP1
VAX2
VENTX
VEZF1
VPS9D1
XPOT
ZBTB24
ZBTB4
ZFHX2
ZFHX3
ZFP1
ZFP91
ZIM2
ZMYND12
ZNF148
ZNF319
ZNF34
ZNF384
ZNF410
ZNF574
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9 interacting genes:
ATPAF2
CREBBP
ERO1A
HOMEZ
MTNR1B
PAX5
POU6F2
ZNF423
ZNF521
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Entrez ID |
11281 |
1879 |
HPRD ID |
10162 |
01256 |
Ensembl ID |
ENSG00000106536
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ENSG00000164330
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Uniprot IDs |
P78424
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B4E2U8
Q9UH73
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PDB IDs |
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3LYR
3MQI
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Enriched GO Terms of Interacting Partners? |
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Tagcloud ? |
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Tagcloud (Difference) ? |
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Tagcloud (Intersection) ? |
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