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ACTN3 and ODF3B
Data Source:
BioGRID
(two hybrid)
ACTN3
ODF3B
Description
actinin alpha 3
outer dense fiber of sperm tails 3B
Image
No pdb structure
GO Annotations
Cellular Component
Cytosol
Actin Filament
Focal Adhesion
Pseudopodium
Extracellular Exosome
Cytoskeleton
Molecular Function
Actin Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Structural Constituent Of Muscle
Identical Protein Binding
Ion Channel Binding
Protein Binding
Biological Process
Regulation Of The Force Of Skeletal Muscle Contraction
Skeletal Muscle Atrophy
Transition Between Fast And Slow Fiber
Response To Denervation Involved In Regulation Of Muscle Adaptation
Muscle Filament Sliding
Regulation Of Apoptotic Process
Negative Regulation Of Glycolytic Process
Focal Adhesion Assembly
Positive Regulation Of Skeletal Muscle Tissue Growth
Negative Regulation Of Calcineurin-NFAT Signaling Cascade
Negative Regulation Of Oxidative Phosphorylation
Negative Regulation Of Cold-induced Thermogenesis
Regulation Of Aerobic Respiration
Positive Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
Pathways
Nephrin family interactions
Striated Muscle Contraction
Drugs
Diseases
GWAS
Bipolar disorder (
21926972
)
Frontotemporal dementia with GRN mutation (
29724592
)
Chronic lymphocytic leukemia (
28165464
)
High light scatter reticulocyte count (
32888494
)
High light scatter reticulocyte percentage of red cells (
32888494
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
29403010
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Monocyte percentage of white cells (
32888494
)
Multiple sclerosis (
31604244
21833088
)
Obesity-related traits (
23251661
)
Red blood cell count (
29403010
32888494
27863252
)
Red blood cell traits (
23222517
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
)
Interacting Genes
61 interacting genes:
ABI3
ACTN1
ACTN2
ACTN4
ADORA2A
ASB9
ATP23
BRCA1
C1orf94
C20orf85
C2CD6
CADPS
CTAG1A
CTAG1B
CTDSP1
CXCL5
DDAH2
DUX1
DUX4L9
ECM1
FAM90A1
GLIS2
HGS
HOXD12
HSF2BP
IVD
KCTD6
KRT6C
LHX3
LINC01554
LNX1
MAGEA6
MICALL2
MYOT
MYOZ1
MYPN
NDUFAB1
NEBL
NKAPD1
NRAP
ODF3B
PCCB
PKP2
PLEKHG2
POU6F2
PPP1R18
PTK6
REL
RNF111
RTP5
SNAI1
SOHLH1
SUMO1P1
SYNPO2L
TRAF1
TRAF2
TRIM29
TTN
USP2
ZNF343
ZNF426
8 interacting genes:
ACTN2
ACTN3
FHL3
HSF2BP
KRTAP3-3
MDFI
MKRN3
SPTA1
Entrez ID
89
440836
HPRD ID
02148
18640
Ensembl ID
ENSG00000248746
ENSG00000177989
Uniprot IDs
A0A087WSZ2
B4DZQ2
Q08043
A1L1A8
A8MYP8
PDB IDs
1TJT
1WKU
3LUE
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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