Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
GLIS2 and TRIM32
Data Source:
BioGRID
(affinity chromatography technology, pull down)
GLIS2
TRIM32
Description
GLIS family zinc finger 2
tripartite motif containing 32
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Non-motile Cilium
Nucleus
Cytoplasm
Cytosol
Striated Muscle Myosin Thick Filament
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Transcription Coactivator Activity
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Myosin Binding
Tat Protein Binding
Translation Initiation Factor Binding
Identical Protein Binding
Ubiquitin Binding
Protein Self-association
Ubiquitin Protein Ligase Activity
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Kidney Development
Cell Differentiation Involved In Kidney Development
Hematopoietic Stem Cell Homeostasis
Positive Regulation Of Protein Localization To Nucleus
Protein Polyubiquitination
Tissue Homeostasis
Ubiquitin-dependent Protein Catabolic Process
Actin Ubiquitination
Response To UV
Protein Ubiquitination
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Regulation Of Type I Interferon Production
Negative Regulation Of Viral Transcription
Response To Tumor Necrosis Factor
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Fat Cell Differentiation
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Cycle
Positive Regulation Of Proteolysis
Positive Regulation Of Transcription, DNA-templated
Muscle Cell Cellular Homeostasis
Negative Regulation Of Fibroblast Proliferation
Positive Regulation Of Neurogenesis
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Striated Muscle Cell Differentiation
Axon Development
Protein K48-linked Ubiquitination
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Interleukin-17-mediated Signaling Pathway
Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production
Positive Regulation Of Cell Motility
Pathways
Regulation of innate immune responses to cytosolic DNA
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
Bardet-Biedl syndrome (BBS)
GWAS
Erectile dysfunction (
30583798
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
26635082
)
Prostate-specific antigen levels (
28139693
)
Estimated glomerular filtration rate (
31015462
)
Interacting Genes
92 interacting genes:
ACTN3
AKAP9
AKT1
ANKRD36B
ARAF
ARID5A
ARNT
BCAR1
BECN1
C19orf54
CBLC
CCND2
CCNE1
CD44
CDK4
CDK6
CDKN2A
CDKN2B
CPSF1
CREM
CRX
CSNK2B
CTBP2
CTNNB1
EPHA2
ERBB2
FAM168B
FGFR4
FOSB
FZR1
GLIS1
GMNN
GOLGA6L9
GPSM1
GPSM2
HGF
HIF1A
KRTAP19-3
KRTAP19-5
KRTAP19-7
KRTAP6-1
KRTAP6-2
KRTAP8-1
LATS2
MAP2K3
MAP2K5
MAP2K6
MAP3K5
MDM2
MDM4
MET
MYC
NF2
NFIC
NME7
NSD3
OIP5
PIK3CA
PLEKHB1
PLEKHB2
POU6F2
PRKAR1B
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RAF1
RASSF1
RBFOX2
RBM11
RBPMS
SHOX
SOX3
SPECC1L
STK11
TEAD2
TENT5A
TERT
TLE5
TRIM32
TSC1
TWIST2
U2AF2
VAC14
VBP1
VENTX
WNK1
WT1
WWOX
XAB2
ZRANB1
63 interacting genes:
ABI2
AKTIP
ATXN1
CLIP4
DERL1
ERGIC3
FADS6
GABARAP
GABARAPL1
GABARAPL2
GEM
GLIS2
GPR137B
HSPA4
ICMT
IQCB1
IRAK1
KCTD9
LCN2
MAP1LC3A
MAP1LC3B
MAP1LC3C
MID2
MOB1A
MYCN
NDRG2
NTAQ1
PDE9A
PELI2
PIAS3
PIAS4
PTCD2
PTPN11
RAB29
RABAC1
RNF208
RNF41
SCGB1A1
SDCBP
STING1
SYT6
TCEANC
TOP1
TRIM23
TRIM27
TRIM5
TRIM72
TTC23
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2U
UBE2V1
UBQLN1
UBQLN2
UBQLN4
VPS11
XIAP
Entrez ID
84662
22954
HPRD ID
12256
03797
Ensembl ID
ENSG00000126603
ENSG00000119401
Uniprot IDs
B3KTH4
Q9BZE0
A0A024R843
Q13049
PDB IDs
2CT2
5FEY
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?