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GLIS2 and KRTAP6-1
Data Source:
BioGRID
(two hybrid)
GLIS2
KRTAP6-1
Description
GLIS family zinc finger 2
keratin associated protein 6-1
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Non-motile Cilium
Cytosol
Intermediate Filament
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Protein Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Kidney Development
Cell Differentiation Involved In Kidney Development
Hematopoietic Stem Cell Homeostasis
Positive Regulation Of Protein Localization To Nucleus
Keratinization
Pathways
Keratinization
Drugs
Diseases
Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS
Erectile dysfunction (
30583798
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
26635082
)
Prostate-specific antigen levels (
28139693
)
Interacting Genes
92 interacting genes:
ACTN3
AKAP9
AKT1
ANKRD36B
ARAF
ARID5A
ARNT
BCAR1
BECN1
C19orf54
CBLC
CCND2
CCNE1
CD44
CDK4
CDK6
CDKN2A
CDKN2B
CPSF1
CREM
CRX
CSNK2B
CTBP2
CTNNB1
EPHA2
ERBB2
FAM168B
FGFR4
FOSB
FZR1
GLIS1
GMNN
GOLGA6L9
GPSM1
GPSM2
HGF
HIF1A
KRTAP19-3
KRTAP19-5
KRTAP19-7
KRTAP6-1
KRTAP6-2
KRTAP8-1
LATS2
MAP2K3
MAP2K5
MAP2K6
MAP3K5
MDM2
MDM4
MET
MYC
NF2
NFIC
NME7
NSD3
OIP5
PIK3CA
PLEKHB1
PLEKHB2
POU6F2
PRKAR1B
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RAF1
RASSF1
RBFOX2
RBM11
RBPMS
SHOX
SOX3
SPECC1L
STK11
TEAD2
TENT5A
TERT
TLE5
TRIM32
TSC1
TWIST2
U2AF2
VAC14
VBP1
VENTX
WNK1
WT1
WWOX
XAB2
ZRANB1
90 interacting genes:
ANAPC11
APOBEC1
ARID5A
BAHD1
BHLHE40
C11orf16
CAMK2A
CAMK2G
CATSPER1
CCDC120
CCDC187
CCDC24
CDA
CELF5
CREB5
CRYAB
CYSRT1
DAZAP2
DTX2
EFEMP1
EVX2
FCHO1
GLIS2
GLIS3
GNE
GPS2
GRN
HELT
HEY2
HHEX
HOXA1
HOXC8
ITIH6
KPRP
KRTAP11-1
KRTAP12-1
KRTAP12-3
KRTAP26-1
KRTAP3-1
KRTAP4-5
KRTAP6-2
KRTAP6-3
LONRF1
MAGED1
MAPK1IP1L
MED25
MEIS2
MGAT5B
MYOZ3
NAF1
NOTO
NTAQ1
OLIG3
OSR2
OTX1
P4HA3
PATZ1
PDIA2
PITX1
PITX2
PLSCR3
PLSCR4
POU1F1
POU4F2
PRR13
PRR35
RBPMS2
RHOXF2
SMARCC1
SMN1
SMN2
SNRPB
TCF7L2
TEKT3
TENT5B
TFAP2D
TLX3
TNIP1
TOLLIP
TRAPPC14
TRIP13
UNC5CL
VAC14
VENTX
VGLL3
VPS37C
ZBTB32
ZC3H10
ZIC1
ZNF414
Entrez ID
84662
337966
HPRD ID
12256
11218
Ensembl ID
ENSG00000126603
ENSG00000184724
Uniprot IDs
B3KTH4
Q9BZE0
Q3LI64
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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