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GLIS2 and PRR20B
Data Source:
BioGRID
(two hybrid)
GLIS2
PRR20B
Description
GLIS family zinc finger 2
proline rich 20B
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Speck
Non-motile Cilium
Molecular Function
Transcription Regulatory Region Sequence-specific DNA Binding
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA-binding Transcription Activator Activity, RNA Polymerase II-specific
Protein Binding
Metal Ion Binding
Sequence-specific Double-stranded DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Central Nervous System Development
Negative Regulation Of DNA-binding Transcription Factor Activity
Negative Regulation Of Smoothened Signaling Pathway
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription From RNA Polymerase II Promoter Involved In Kidney Development
Cell Differentiation Involved In Kidney Development
Hematopoietic Stem Cell Homeostasis
Positive Regulation Of Protein Localization To Nucleus
Pathways
Drugs
Diseases
Nephronophthisis-medullary cystic kidney disease, including; Nephronophthisis (NPH) ; Nephronophthisis-like nephropathy 1; Medullary cystic kidney disease 1; Medullary cystic kidney disease 2 (MSKD2)
GWAS
Erectile dysfunction (
30583798
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
26635082
)
Prostate-specific antigen levels (
28139693
)
Mosaic loss of chromosome Y (Y chromosome dosage) (
31624269
)
Interacting Genes
92 interacting genes:
ACTN3
AKAP9
AKT1
ANKRD36B
ARAF
ARID5A
ARNT
BCAR1
BECN1
C19orf54
CBLC
CCND2
CCNE1
CD44
CDK4
CDK6
CDKN2A
CDKN2B
CPSF1
CREM
CRX
CSNK2B
CTBP2
CTNNB1
EPHA2
ERBB2
FAM168B
FGFR4
FOSB
FZR1
GLIS1
GMNN
GOLGA6L9
GPSM1
GPSM2
HGF
HIF1A
KRTAP19-3
KRTAP19-5
KRTAP19-7
KRTAP6-1
KRTAP6-2
KRTAP8-1
LATS2
MAP2K3
MAP2K5
MAP2K6
MAP3K5
MDM2
MDM4
MET
MYC
NF2
NFIC
NME7
NSD3
OIP5
PIK3CA
PLEKHB1
PLEKHB2
POU6F2
PRKAR1B
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
RAF1
RASSF1
RBFOX2
RBM11
RBPMS
SHOX
SOX3
SPECC1L
STK11
TEAD2
TENT5A
TERT
TLE5
TRIM32
TSC1
TWIST2
U2AF2
VAC14
VBP1
VENTX
WNK1
WT1
WWOX
XAB2
ZRANB1
89 interacting genes:
ABI2
ANKHD1
ARID5A
ATXN1
BANP
BEND2
BHLHE40
BICRAL
C10orf55
C1orf94
C3orf36
CABP2
CCNK
CDC37
CELF4
DAZAP2
DMRT3
DVL3
EIF4ENIF1
ESRP1
FAM168A
FAM222B
FAM9A
FOXH1
FOXP3
GLIS2
GTF2A1
HIVEP1
HLX
HYPK
KRTAP19-1
KRTAP19-5
LASP1
MAGED1
MBNL3
NCK2
NFYC
NOTCH3
NTAQ1
OXER1
PATZ1
PHF1
PITX1
POGZ
POU2F1
POU6F2
PRR20A
PRR20C
PRR20D
PRR20E
PRR34
PRR35
PTTG2
RBM23
RBM42
RBPMS
RBPMS2
RHOXF2
RIPPLY1
RNF4
ROR2
SAMD11
SH3RF1
SIAH1
SMAP1
SNRPB
SNRPC
SP4
SRPK2
TBX3
TBX6
TCF7L2
TFG
THAP1
TIAL1
TLX3
TOLLIP
TPRX1
TRIM35
VAC14
VENTX
VEZF1
VPS37C
YPEL3
ZBTB32
ZC3H10
ZCCHC14
ZNF385C
ZNF683
Entrez ID
84662
729233
HPRD ID
12256
19668
Ensembl ID
ENSG00000126603
ENSG00000204918
Uniprot IDs
B3KTH4
Q9BZE0
P86478
P86479
P86480
P86481
P86496
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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