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TRIM32 and PTCD2
Data Source:
BioGRID
(two hybrid)
TRIM32
PTCD2
Description
tripartite motif containing 32
pentatricopeptide repeat domain 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Striated Muscle Myosin Thick Filament
Mitochondrion
Molecular Function
Transcription Coactivator Activity
RNA Binding
Ubiquitin-protein Transferase Activity
Protein Binding
Zinc Ion Binding
Myosin Binding
Tat Protein Binding
Translation Initiation Factor Binding
Identical Protein Binding
Ubiquitin Binding
Protein Self-association
Ubiquitin Protein Ligase Activity
RNA Binding
Protein Binding
Biological Process
Protein Polyubiquitination
Tissue Homeostasis
Ubiquitin-dependent Protein Catabolic Process
Actin Ubiquitination
Response To UV
Protein Ubiquitination
Positive Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Regulation Of Type I Interferon Production
Negative Regulation Of Viral Transcription
Response To Tumor Necrosis Factor
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Fat Cell Differentiation
Positive Regulation Of Neuron Differentiation
Positive Regulation Of Protein Catabolic Process
Positive Regulation Of Cell Cycle
Positive Regulation Of Proteolysis
Positive Regulation Of Transcription, DNA-templated
Muscle Cell Cellular Homeostasis
Negative Regulation Of Fibroblast Proliferation
Positive Regulation Of Neurogenesis
Positive Regulation Of DNA-binding Transcription Factor Activity
Positive Regulation Of NF-kappaB Transcription Factor Activity
Positive Regulation Of Striated Muscle Cell Differentiation
Axon Development
Protein K48-linked Ubiquitination
Negative Regulation Of Viral Release From Host Cell
Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Positive Regulation Of Interleukin-17-mediated Signaling Pathway
Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production
Positive Regulation Of Cell Motility
Kidney Development
Liver Development
MRNA Processing
Mitochondrion Organization
Multicellular Organism Development
Regulation Of Gene Expression
Muscle Fiber Development
Regulation Of MRNA Processing
Ventricular Cardiac Muscle Tissue Morphogenesis
Pathways
Regulation of innate immune responses to cytosolic DNA
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Bardet-Biedl syndrome (BBS)
GWAS
Estimated glomerular filtration rate (
31015462
)
Apolipoprotein A1 levels (
32203549
)
Asthma (
32296059
)
Asthma (childhood onset) (
31036433
)
Glaucoma (
31959993
)
Intraocular pressure (
29617998
29785010
31959993
30054594
)
Pulse pressure (
27841878
)
Refractive error (
32231278
)
Interacting Genes
63 interacting genes:
ABI2
AKTIP
ATXN1
CLIP4
DERL1
ERGIC3
FADS6
GABARAP
GABARAPL1
GABARAPL2
GEM
GLIS2
GPR137B
HSPA4
ICMT
IQCB1
IRAK1
KCTD9
LCN2
MAP1LC3A
MAP1LC3B
MAP1LC3C
MID2
MOB1A
MYCN
NDRG2
NTAQ1
PDE9A
PELI2
PIAS3
PIAS4
PTCD2
PTPN11
RAB29
RABAC1
RNF208
RNF41
SCGB1A1
SDCBP
STING1
SYT6
TCEANC
TOP1
TRIM23
TRIM27
TRIM5
TRIM72
TTC23
UBC
UBE2D1
UBE2D2
UBE2D3
UBE2E1
UBE2E2
UBE2E3
UBE2N
UBE2U
UBE2V1
UBQLN1
UBQLN2
UBQLN4
VPS11
XIAP
4 interacting genes:
MID1
MID2
TRIM32
USP49
Entrez ID
22954
79810
HPRD ID
03797
15193
Ensembl ID
ENSG00000119401
ENSG00000049883
Uniprot IDs
A0A024R843
Q13049
A0A024RAM6
B3KPU6
B7Z8R2
F6S289
Q8WV60
PDB IDs
2CT2
5FEY
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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