TRIM32 and TCEANC

Data Source:
BioGRID (two hybrid)

		TRIM32	TCEANC
Description		tripartite motif containing 32	transcription elongation factor A N-terminal and central domain containing
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Striated Muscle Myosin Thick Filament	Nucleus
	Molecular Function	Transcription Coactivator Activity RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Myosin Binding Tat Protein Binding Translation Initiation Factor Binding Identical Protein Binding Ubiquitin Binding Protein Self-association Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Protein Polyubiquitination Tissue Homeostasis Ubiquitin-dependent Protein Catabolic Process Actin Ubiquitination Response To UV Protein Ubiquitination Positive Regulation Of Cell Growth Positive Regulation Of Cell Migration Regulation Of Type I Interferon Production Negative Regulation Of Viral Transcription Response To Tumor Necrosis Factor Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Innate Immune Response Fat Cell Differentiation Positive Regulation Of Neuron Differentiation Positive Regulation Of Protein Catabolic Process Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Positive Regulation Of Transcription, DNA-templated Muscle Cell Cellular Homeostasis Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Neurogenesis Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Striated Muscle Cell Differentiation Axon Development Protein K48-linked Ubiquitination Negative Regulation Of Viral Release From Host Cell Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Positive Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Interleukin-17-mediated Signaling Pathway Positive Regulation Of Chemokine (C-C Motif) Ligand 20 Production Positive Regulation Of Cell Motility	Transcription, DNA-templated
Pathways		Regulation of innate immune responses to cytosolic DNA Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS		Estimated glomerular filtration rate ( 31015462)
Interacting Genes		63 interacting genes: ABI2 AKTIP ATXN1 CLIP4 DERL1 ERGIC3 FADS6 GABARAP GABARAPL1 GABARAPL2 GEM GLIS2 GPR137B HSPA4 ICMT IQCB1 IRAK1 KCTD9 LCN2 MAP1LC3A MAP1LC3B MAP1LC3C MID2 MOB1A MYCN NDRG2 NTAQ1 PDE9A PELI2 PIAS3 PIAS4 PTCD2 PTPN11 RAB29 RABAC1 RNF208 RNF41 SCGB1A1 SDCBP STING1 SYT6 TCEANC TOP1 TRIM23 TRIM27 TRIM5 TRIM72 TTC23 UBC UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2N UBE2U UBE2V1 UBQLN1 UBQLN2 UBQLN4 VPS11 XIAP	139 interacting genes: ADARB1 AKAP9 ANAPC11 APP ATXN1 AXIN2 BICD2 BRCA1 C1QTNF2 C8orf34 CARD9 CBY2 CCDC102B CCDC138 CCDC33 CCDC85B CCNC CDR2L CEP70 CEP76 CRACR2B CREB3L3 CSRNP1 CTAG1A CTAG1B CYSRT1 DAB1 DISC1 DMAP1 DTX3 DVL3 DYNLT1 EVI5 FAM217B FAM9B FANCG FBXO25 FCHO1 FSD2 GOLGA2 GOLGA6L9 HES7 HIP1 HMBOX1 HOMEZ HOOK2 IGF1 IKBKG IKZF2 IKZF3 KATNBL1 KCTD6 KCTD7 KIAA1958 KIF16B KIFC3 KLHL12 KRT31 KRT35 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-3 KRTAP4-2 KRTAP5-9 L3MBTL3 LDOC1 LHX2 LHX3 LIN7B LMNA LSM14B LURAP1 MAGEA11 MCC MCIDAS MDFI MEOX1 MEOX2 MID1 MID2 MTUS2 MYF5 MYLIP NAB2 NECAB1 NEDD4 NINL OBI1 OOEP OSBPL3 PICK1 PLEKHF2 PNMA1 PNMA5 PXN RAD54B RNF41 RUBCN SIPA1L2 SORBS3 SSNA1 STRN3 STX1A STX4 TARBP2 TCP10L THAP1 TLE5 TMCO2 TNIP1 TNIP3 TRAF2 TRIM23 TRIM27 TRIM32 TRIM35 TRIM37 TRIM41 TRIM54 UBXN11 USH1G USHBP1 VAC14 VBP1 VPS52 YWHAE ZBTB14 ZBTB39 ZBTB9 ZFYVE26 ZKSCAN7 ZNF276 ZNF655 ZNF670 ZNF688 ZNF837 ZRANB1
Entrez ID		22954	170082
HPRD ID		03797	19501
Ensembl ID		ENSG00000119401	ENSG00000176896
Uniprot IDs		A0A024R843 Q13049	A8K5F6 B4DG85 Q8N8B7
PDB IDs		2CT2 5FEY
Enriched GO Terms of Interacting Partners?
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