DSN1 and NSL1

Data Source:
HPRD (in vitro)

		DSN1	NSL1
Description		DSN1 component of MIS12 kinetochore complex	NSL1 component of MIS12 kinetochore complex
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GO Annotations	Cellular Component	MIS12/MIND Type Complex Kinetochore Condensed Chromosome Kinetochore Nuclear MIS12/MIND Complex Condensed Nuclear Chromosome Inner Kinetochore Fibrillar Center Extracellular Region Nucleoplasm Nucleolus Cytosol Nuclear Body Azurophil Granule Lumen	MIS12/MIND Type Complex Condensed Chromosome Kinetochore Cytosol Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Neutrophil Degranulation Cell Division	Mitotic Sister Chromatid Segregation Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Neutrophil degranulation Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Factor VII activity ( 30642921) Hallux valgus ( 32131869)
Interacting Genes		12 interacting genes: AIMP2 APP CBX3 CBX5 HGS KNL1 MIS12 NSL1 PIK3R3 PMF1 SUGT1 ZWINT	9 interacting genes: CBX1 CBX3 CBX5 DSN1 G6PC1 HSP90AA1 LRRK2 MIS12 SUGT1
Entrez ID		79980	25936
HPRD ID		16455	12378
Ensembl ID		ENSG00000149636	ENSG00000117697
Uniprot IDs		A8K3X3 Q9H410	Q53FM2 Q5SY74 Q96IY1
PDB IDs		5LSI 5LSJ 5LSK	4NF9 5LSI 5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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