NSL1 and CBX1

Data Source:
BioGRID (affinity chromatography technology, two hybrid)

		NSL1	CBX1
Description		NSL1 component of MIS12 kinetochore complex	chromobox 1
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GO Annotations	Cellular Component	MIS12/MIND Type Complex Condensed Chromosome Kinetochore Cytosol Nuclear Speck	Chromosome, Centromeric Region Chromosome, Telomeric Region Chromatin Heterochromatin Female Pronucleus Male Pronucleus Nucleus Nucleoplasm Pericentric Heterochromatin Spindle Chromocenter Site Of DNA Damage
	Molecular Function	Protein Binding	Chromatin Binding Protein Binding Enzyme Binding Identical Protein Binding Histone Methyltransferase Binding
	Biological Process	Mitotic Sister Chromatid Segregation Cell Division	Cellular Response To DNA Damage Stimulus Negative Regulation Of Transcription, DNA-templated
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	HCMV Early Events
Drugs
Diseases
GWAS			Body mass index ( 26426971 20935630) Generalized epilepsy ( 22949513)
Interacting Genes		9 interacting genes: CBX1 CBX3 CBX5 DSN1 G6PC1 HSP90AA1 LRRK2 MIS12 SUGT1	36 interacting genes: ABI3BP ARL5A ATXN7L2 BAHD1 BARD1 BRCA1 CBX3 CBX5 CHAF1A DNMT1 DNMT3A DNMT3B EMSY H1-4 H3-4 H3C1 H3C3 HECW2 HSPB1 KLF11 LNX1 LRIF1 NR2F6 NSL1 PCNA PIM1 RB1 RPL12 SP100 SUV39H1 TRIM24 TRIM28 UCHL1 VHL VTN ZNF280C
Entrez ID		25936	10951
HPRD ID		12378	05149
Ensembl ID		ENSG00000117697	ENSG00000108468
Uniprot IDs		Q53FM2 Q5SY74 Q96IY1	P83916 Q6IBN6
PDB IDs		4NF9 5LSI 5LSJ 5LSK	2FMM 3F2U 3Q6S 5T1G 6D07 6D08
Enriched GO Terms of Interacting Partners?
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