DSN1 and ZWINT

Data Source:
HPRD (in vivo)

		DSN1	ZWINT
Description		DSN1 component of MIS12 kinetochore complex	ZW10 interacting kinetochore protein
Image			No pdb structure
GO Annotations	Cellular Component	MIS12/MIND Type Complex Kinetochore Condensed Chromosome Kinetochore Nuclear MIS12/MIND Complex Condensed Nuclear Chromosome Inner Kinetochore Fibrillar Center Extracellular Region Nucleoplasm Nucleolus Cytosol Nuclear Body Azurophil Granule Lumen	Kinetochore Condensed Chromosome Kinetochore Nucleoplasm Cytoplasm Cytosol Nuclear Body Dendrite
	Molecular Function	Protein Binding	Protein Binding Protein N-terminus Binding
	Biological Process	Mitotic Sister Chromatid Segregation Neutrophil Degranulation Cell Division	Mitotic Sister Chromatid Segregation Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Cell Division Establishment Of Localization In Cell
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Neutrophil degranulation Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Factor VII activity ( 30642921) Hallux valgus ( 32131869)	Cardiac hypertrophy ( 21348951) Erosive tooth wear (severe vs non-severe) ( 29898447) Erosive tooth wear (severe vs none or mild) ( 29898447) Liver fibrosis (total hepatic collagen content) ( 32953199)
Interacting Genes		12 interacting genes: AIMP2 APP CBX3 CBX5 HGS KNL1 MIS12 NSL1 PIK3R3 PMF1 SUGT1 ZWINT	17 interacting genes: APP BCAS2 BFSP1 CCHCR1 CLU DSN1 FAM90A1 KRT75 LIG4 MAFB MIS12 MSGN1 NDC80 NUP54 PHAX TSG101 ZW10
Entrez ID		79980	11130
HPRD ID		16455	18366
Ensembl ID		ENSG00000149636	ENSG00000122952
Uniprot IDs		A8K3X3 Q9H410	O95229
PDB IDs		5LSI 5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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