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DSN1

Description DSN1 component of MIS12 kinetochore complex
Image
GO Annotations Cellular Component
  • MIS12/MIND Type Complex
  • Kinetochore
  • Condensed Chromosome Kinetochore
  • Nuclear MIS12/MIND Complex
  • Condensed Nuclear Chromosome Inner Kinetochore
  • Fibrillar Center
  • Extracellular Region
  • Nucleoplasm
  • Nucleolus
  • Cytosol
  • Nuclear Body
  • Azurophil Granule Lumen
Molecular Function
  • Protein Binding
Biological Process
  • Mitotic Sister Chromatid Segregation
  • Neutrophil Degranulation
  • Cell Division
Pathways
  • Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
  • Separation of Sister Chromatids
  • Resolution of Sister Chromatid Cohesion
  • RHO GTPases Activate Formins
  • Neutrophil degranulation
  • Mitotic Prometaphase
  • EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS
  • Factor VII activity ( 30642921)
  • Hallux valgus ( 32131869)
Interacting Genes 12 interacting genes: AIMP2 APP CBX3 CBX5 HGS KNL1 MIS12 NSL1 PIK3R3 PMF1 SUGT1 ZWINT
Entrez ID 79980
HPRD ID 16455
Ensembl ID ENSG00000149636
Uniprot IDs A8K3X3 Q9H410
PDB IDs 5LSI 5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025