DSN1 and SUGT1

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down)

		DSN1	SUGT1
Description		DSN1 component of MIS12 kinetochore complex	SGT1 homolog, MIS12 kinetochore complex assembly cochaperone
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GO Annotations	Cellular Component	MIS12/MIND Type Complex Kinetochore Condensed Chromosome Kinetochore Nuclear MIS12/MIND Complex Condensed Nuclear Chromosome Inner Kinetochore Fibrillar Center Extracellular Region Nucleoplasm Nucleolus Cytosol Nuclear Body Azurophil Granule Lumen	Ubiquitin Ligase Complex Kinetochore Nucleus Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Neutrophil Degranulation Cell Division	Mitotic Cell Cycle Regulation Of Protein Stability Positive Regulation By Host Of Symbiont Catalytic Activity Protein Stabilization
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Neutrophil degranulation Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS		Factor VII activity ( 30642921) Hallux valgus ( 32131869)
Interacting Genes		12 interacting genes: AIMP2 APP CBX3 CBX5 HGS KNL1 MIS12 NSL1 PIK3R3 PMF1 SUGT1 ZWINT	17 interacting genes: BUB3 CSNK2A1 DSN1 HSP90AA1 HSPA4 MIS12 NR4A1 NSL1 PAXIP1 PHLPP1 PLK1 PMF1 PTGER4 S100A6 S100B S100P SKP1
Entrez ID		79980	10910
HPRD ID		16455	09160
Ensembl ID		ENSG00000149636	ENSG00000165416
Uniprot IDs		A8K3X3 Q9H410	A8K7W3 B4DYC6 Q9Y2Z0
PDB IDs		5LSI 5LSJ 5LSK	1RL1
Enriched GO Terms of Interacting Partners?
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