NSL1 and DSN1

Data Source:
HPRD (in vitro)

		NSL1	DSN1
Description		NSL1 component of MIS12 kinetochore complex	DSN1 component of MIS12 kinetochore complex
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GO Annotations	Cellular Component	MIS12/MIND Type Complex Condensed Chromosome Kinetochore Cytosol Nuclear Speck	MIS12/MIND Type Complex Kinetochore Condensed Chromosome Kinetochore Nuclear MIS12/MIND Complex Condensed Nuclear Chromosome Inner Kinetochore Fibrillar Center Extracellular Region Nucleoplasm Nucleolus Cytosol Nuclear Body Azurophil Granule Lumen
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Cell Division	Mitotic Sister Chromatid Segregation Neutrophil Degranulation Cell Division
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Neutrophil degranulation Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS			Factor VII activity ( 30642921) Hallux valgus ( 32131869)
Interacting Genes		9 interacting genes: CBX1 CBX3 CBX5 DSN1 G6PC1 HSP90AA1 LRRK2 MIS12 SUGT1	12 interacting genes: AIMP2 APP CBX3 CBX5 HGS KNL1 MIS12 NSL1 PIK3R3 PMF1 SUGT1 ZWINT
Entrez ID		25936	79980
HPRD ID		12378	16455
Ensembl ID		ENSG00000117697	ENSG00000149636
Uniprot IDs		Q53FM2 Q5SY74 Q96IY1	A8K3X3 Q9H410
PDB IDs		4NF9 5LSI 5LSJ 5LSK	5LSI 5LSJ 5LSK
Enriched GO Terms of Interacting Partners?
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