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MTF2

Description metal response element binding transcription factor 2
Image
GO Annotations Cellular Component
  • Nucleus
  • Nucleoplasm
  • Cytoplasm
  • Focal Adhesion
  • ESC/E(Z) Complex
Molecular Function
  • RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding
  • RNA Polymerase II Transcription Corepressor Binding
  • DNA Binding
  • Chromatin Binding
  • Methylated Histone Binding
  • Metal Ion Binding
Biological Process
  • Negative Regulation Of Transcription By RNA Polymerase II
  • Chromatin Organization
  • Regulation Of Transcription, DNA-templated
  • Segment Specification
  • Stem Cell Population Maintenance
  • Negative Regulation Of Gene Expression, Epigenetic
  • Positive Regulation Of Transcription By RNA Polymerase II
  • Stem Cell Differentiation
  • Negative Regulation Of Histone H3-K27 Methylation
  • Positive Regulation Of Histone H3-K27 Methylation
  • Cellular Response To Leukemia Inhibitory Factor
Pathways
  • PRC2 methylates histones and DNA
Drugs
Diseases
GWAS
  • Bitter alcoholic beverage consumption ( 31046077)
  • Chronotype ( 30696823)
  • Eosinophil counts ( 32888494)
  • Eosinophil percentage of white cells ( 32888494)
  • Plasma clusterin levels ( 26545630)
  • Response to lurasidone in schizophrenia ( 29730043)
  • Triglyceride levels ( 32154731)
Interacting Genes 12 interacting genes: CDKN2D CREB1 GPRASP1 GSK3B KDM1A PIK3R3 PRKD2 PRMT6 SMAD3 SUV39H1 SUV39H2 TMED9
Entrez ID 22823
HPRD ID 14342
Ensembl ID ENSG00000143033
Uniprot IDs B4DZ69 B4DZG1 Q7Z534 Q9Y483
PDB IDs 5XFR
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025