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CCL5 and CXCL9
Data Source:
BioGRID
(pull down)
CCL5
CXCL9
Description
C-C motif chemokine ligand 5
C-X-C motif chemokine ligand 9
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Molecular Function
Phosphatidylinositol Phospholipase C Activity
Protein Kinase Activity
Protein Binding
Chemokine Activity
Phospholipase Activator Activity
Receptor Signaling Protein Tyrosine Kinase Activator Activity
CCR1 Chemokine Receptor Binding
CCR4 Chemokine Receptor Binding
CCR5 Chemokine Receptor Binding
Chemoattractant Activity
Chemokine Receptor Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Self-association
Chemokine Receptor Antagonist Activity
CCR Chemokine Receptor Binding
Cytokine Activity
Protein Binding
Chemokine Activity
CXCR Chemokine Receptor Binding
CXCR3 Chemokine Receptor Binding
Biological Process
MAPK Cascade
Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Regulation Of Chronic Inflammatory Response
Protein Phosphorylation
Calcium Ion Transport
Cellular Calcium Ion Homeostasis
Exocytosis
Chemotaxis
Inflammatory Response
Leukocyte Cell-cell Adhesion
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Response To Toxic Substance
Positive Regulation Of Activation Of Janus Kinase Activity
Positive Regulation Of Macrophage Chemotaxis
Positive Regulation Of T Cell Chemotaxis
Positive Regulation Of Phosphatidylinositol 3-kinase Signaling
Positive Regulation Of Smooth Muscle Cell Migration
Cytokine-mediated Signaling Pathway
Positive Regulation Of Cell Migration
Neutrophil Chemotaxis
Positive Regulation Of Cellular Biosynthetic Process
Activation Of Phospholipase D Activity
Lipopolysaccharide-mediated Signaling Pathway
Positive Regulation Of Cell-cell Adhesion Mediated By Integrin
Positive Regulation Of Homotypic Cell-cell Adhesion
Positive Regulation Of T Cell Proliferation
Neutrophil Activation
Positive Regulation Of Phosphorylation
Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein
Protein Kinase B Signaling
Positive Regulation Of GTPase Activity
Negative Regulation By Host Of Viral Transcription
Cellular Response To Fibroblast Growth Factor Stimulus
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Viral Genome Replication
Positive Regulation Of Innate Immune Response
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cell Adhesion
Positive Regulation Of Translational Initiation
Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT
Eosinophil Chemotaxis
Macrophage Chemotaxis
Lymphocyte Chemotaxis
Positive Regulation Of Smooth Muscle Cell Proliferation
Regulation Of Insulin Secretion
Regulation Of T Cell Activation
Positive Chemotaxis
Positive Regulation Of Calcium Ion Transport
Positive Regulation Of Protein Tyrosine Kinase Activity
Chemokine-mediated Signaling Pathway
Negative Regulation Of Chemokine-mediated Signaling Pathway
Negative Regulation Of T Cell Apoptotic Process
Positive Regulation Of T Cell Apoptotic Process
Positive Regulation Of ERK1 And ERK2 Cascade
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Cellular Response To Organic Cyclic Compound
Positive Regulation Of Monocyte Chemotaxis
Regulation Of Neuron Death
Positive Regulation Of T Cell Migration
Positive Regulation Of Natural Killer Cell Chemotaxis
Chemotaxis
Defense Response
Inflammatory Response
Cellular Defense Response
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Neutrophil Chemotaxis
Regulation Of Cell Population Proliferation
Positive Regulation Of Myoblast Differentiation
Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
Defense Response To Virus
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Cellular Response To Lipopolysaccharide
Positive Regulation Of Myoblast Fusion
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Heparin Disaccharide I-S
Heparin Disaccharide Iii-S
Diseases
GWAS
Blood protein levels (
30072576
28240269
)
Blood protein levels (
28240269
)
Hippocampal volume (
29274321
)
Neonatal cytokine/chemokine levels (fetal genetic effect) (
30134952
)
Interacting Genes
55 interacting genes:
ACKR1
ACKR2
ACKR4
APC
BAG4
BCAR3
CCL11
CCL13
CCL16
CCL17
CCL2
CCL20
CCL21
CCL24
CCL25
CCL26
CCL27
CCL28
CCR1
CCR3
CCR4
CCR5
CHEK2
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCL6
CXCL8
CXCL9
DPP4
EDC4
FZR1
GRB2
IGFBP7
KRAS
PALB2
PF4
PHB
PIGR
PPBP
PTPN1
RANGAP1
RELA
SDC1
SDC4
SLC2A5
TGFB1
TRIP6
VCAN
WT1
XCL1
XCL2
76 interacting genes:
AMIGO1
AQP6
ATP1B4
BMF
BSCL2
BTNL9
C16orf92
CCL11
CCL13
CCL2
CCL21
CCL26
CCL28
CCL5
CCR3
CD33
CHODL
CLDN2
CLDN5
CLDN7
CLEC17A
CLEC2D
CLEC4E
CLEC7A
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCR3
DPP4
EPGN
EREG
FBXO7
FCGR2A
FFAR2
FNDC9
FUT7
GJB1
GORAB
GPR42
IFNGR2
ITM2C
KASH5
KIR2DL3
LDLRAD1
LEUTX
LRRC25
LSMEM2
MR1
MTIF3
MUC1
NEMP1
PAX8
PF4
PPBP
PTPN5
RHCG
SFTPC
SLC10A1
SLC39A1
SSMEM1
SUSD3
SYNE4
TM4SF18
TMED5
TMEM106C
TMEM234
TMEM237
TMEM31
TMPRSS2
TNFSF14
TNFSF8
TSPAN18
XCL1
Entrez ID
6352
4283
HPRD ID
01751
03416
Ensembl ID
ENSG00000271503
ENSG00000138755
Uniprot IDs
A0A494C1Q1
D0EI67
P13501
Q07325
PDB IDs
1B3A
1EQT
1HRJ
1RTN
1RTO
1U4L
1U4M
1U4P
1U4R
2L9H
2VXW
5CMD
5COY
5DNF
5L2U
5UIW
6AEZ
6C6D
6FGP
6LOG
6STK
Enriched GO Terms of Interacting Partners
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