CXCL9 and CLEC4E

Data Source:
BioGRID (two hybrid)

		CXCL9	CLEC4E
Description		C-X-C motif chemokine ligand 9	C-type lectin domain family 4 member E
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space External Side Of Plasma Membrane	Plasma Membrane Membrane Integral Component Of Membrane
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CXCR Chemokine Receptor Binding CXCR3 Chemokine Receptor Binding	Calcium Ion Binding Protein Binding Carbohydrate Binding Pattern Recognition Receptor Activity
	Biological Process	Chemotaxis Defense Response Inflammatory Response Cellular Defense Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Neutrophil Chemotaxis Regulation Of Cell Population Proliferation Positive Regulation Of Myoblast Differentiation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Defense Response To Virus Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Positive Regulation Of Myoblast Fusion	Pattern Recognition Receptor Signaling Pathway Stimulatory C-type Lectin Receptor Signaling Pathway Innate Immune Response
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Dectin-2 family Dectin-2 family
Drugs			Cholesterol
Diseases
GWAS		Blood protein levels ( 28240269) Hippocampal volume ( 29274321) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952)	Takayasu arteritis ( 25604533)
Interacting Genes		76 interacting genes: AMIGO1 AQP6 ATP1B4 BMF BSCL2 BTNL9 C16orf92 CCL11 CCL13 CCL2 CCL21 CCL26 CCL28 CCL5 CCR3 CD33 CHODL CLDN2 CLDN5 CLDN7 CLEC17A CLEC2D CLEC4E CLEC7A CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL2 CXCR3 DPP4 EPGN EREG FBXO7 FCGR2A FFAR2 FNDC9 FUT7 GJB1 GORAB GPR42 IFNGR2 ITM2C KASH5 KIR2DL3 LDLRAD1 LEUTX LRRC25 LSMEM2 MR1 MTIF3 MUC1 NEMP1 PAX8 PF4 PPBP PTPN5 RHCG SFTPC SLC10A1 SLC39A1 SSMEM1 SUSD3 SYNE4 TM4SF18 TMED5 TMEM106C TMEM234 TMEM237 TMEM31 TMPRSS2 TNFSF14 TNFSF8 TSPAN18 XCL1	4 interacting genes: CXCL9 FAM3C FCER1G NKG7
Entrez ID		4283	26253
HPRD ID		03416	13075
Ensembl ID		ENSG00000138755	ENSG00000166523
Uniprot IDs		Q07325	F5H5X7 Q9ULY5
PDB IDs			3WH2 3WH3
Enriched GO Terms of Interacting Partners?
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