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RPA2 and CRMP1
Data Source:
HPRD
(two hybrid)
RPA2
CRMP1
Description
replication protein A2
collapsin response mediator protein 1
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
Nuclear Body
PML Body
Site Of Double-strand Break
Nucleus
Centrosome
Spindle
Cytosol
Growth Cone
Midbody
Perikaryon
Molecular Function
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Enzyme Binding
Protein Phosphatase Binding
Ubiquitin Protein Ligase Binding
Protein N-terminus Binding
G-rich Strand Telomeric DNA Binding
Dihydropyrimidinase Activity
Protein Binding
Filamin Binding
Identical Protein Binding
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Replication
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Regulation Of Double-strand Break Repair Via Homologous Recombination
Translesion Synthesis
Mitotic G1 DNA Damage Checkpoint
Telomere Maintenance Via Semi-conservative Replication
Nucleotide-excision Repair, DNA Incision
Protein Localization To Chromosome
Interstrand Cross-link Repair
Error-prone Translesion Synthesis
DNA Damage Response, Detection Of DNA Damage
Error-free Translesion Synthesis
Regulation Of Cellular Response To Heat
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of DNA Damage Checkpoint
Microtubule Cytoskeleton Organization
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Catabolic Process
Nervous System Development
Axon Guidance
Negative Regulation Of Neuron Projection Development
Negative Regulation Of Actin Filament Binding
Pathways
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Removal of the Flap Intermediate from the C-strand
Activation of ATR in response to replication stress
Regulation of HSF1-mediated heat shock response
HSF1 activation
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Formation of Incision Complex in GG-NER
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Fanconi Anemia Pathway
Regulation of TP53 Activity through Phosphorylation
Activation of the pre-replicative complex
Removal of the Flap Intermediate
G2/M DNA damage checkpoint
Meiotic recombination
CRMPs in Sema3A signaling
Drugs
Diseases
GWAS
HDL cholesterol levels (
32203549
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
White blood cell count (
32888494
)
Blood trace element (Zn levels) (
23720494
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Metabolite levels (
23823483
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
63 interacting genes:
ACP5
AKAP9
APP
ATM
CALCOCO2
CASK
CCNC
CCNO
CDC5L
CDK1
CEP126
CFB
COPS6
CRMP1
DMRTB1
EEF1A1
EIF4G2
ERCC1
ERCC4
GAPDH
GOLM1
HERPUD1
HNRNPUL1
HUS1
LNX2
LRIF1
MARK2
MCM2
MCM5
MED1
MED31
MEN1
NDEL1
ORC1
ORC2
ORC4
ORC5
PCM1
PPP4C
PRC1
PRKCI
PRKDC
RAD1
RAD51
RAD52
RAD9A
RBM14
RBM48
RPA1
RPA3
RPLP1
SDF4
SERTAD3
SLC17A9
STAT3
TLE1
TUBB2A
UNC119
UNG
UTP14A
XPA
YWHAE
ZBTB14
80 interacting genes:
AGR2
ALDH2
AMFR
ANXA7
AP3M1
ARL15
AXIN1
BID
BTBD2
CACNA1A
CCDC106
CCL18
CCT7
CDK5RAP2
CDK5RAP3
DDX18
DNAJB11
DPYSL2
DPYSL3
DUSP4
EEF1D
EIF2S2
EPN1
EXOSC8
FAS
FTH1
FUBP1
FXR1
GNE
GOLGA2
HDHD2
HGS
HMGB1
HNRNPH1
HNRNPH3
HNRNPUL1
HSPE1
HTT
IL33
KLHL20
LRRC1
LRRK2
LSM2
MAP3K20
MAPK8IP2
MCM3AP
MOB4
MRPS12
NAT9
NDUFV2
NVL
PAFAH1B3
PFN1
PLA2G2A
PMF1
PPP1R8
PSMD11
RACK1
RGL2
RGS2
ROCK1
RPA2
RPS6KA5
RTN4
SAT1
SEPHS1
SERPINB9
SNRPG
SPRY2
SRC
TFG
TK1
TRIP13
TSC22D1
UBE2A
UBE2B
VCP
VIM
YAE1
ZNF24
Entrez ID
6118
1400
HPRD ID
01566
03913
Ensembl ID
ENSG00000117748
ENSG00000072832
Uniprot IDs
B4DUL2
P15927
B3KT07
B3KV96
E9PD68
Q14194
Q96I11
X5DNI1
PDB IDs
1DPU
1L1O
1QUQ
1Z1D
2PI2
2PQA
2Z6K
3KDF
4MQV
4OU0
4B3Z
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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