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RPA2 and CASK
Data Source:
BioGRID
(two hybrid)
RPA2
CASK
Description
replication protein A2
calcium/calmodulin dependent serine protein kinase
Image
GO Annotations
Cellular Component
Chromosome, Telomeric Region
Chromatin
Nucleus
Nucleoplasm
DNA Replication Factor A Complex
Nuclear Body
PML Body
Site Of Double-strand Break
Basement Membrane
Nuclear Lamina
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Cell-cell Junction
Focal Adhesion
Actin Cytoskeleton
Nuclear Matrix
Presynaptic Membrane
Ciliary Membrane
Molecular Function
Damaged DNA Binding
Single-stranded DNA Binding
Protein Binding
Enzyme Binding
Protein Phosphatase Binding
Ubiquitin Protein Ligase Binding
Protein N-terminus Binding
G-rich Strand Telomeric DNA Binding
Guanylate Kinase Activity
Protein Serine/threonine Kinase Activity
Protein Binding
Calmodulin Binding
ATP Binding
Protein Serine Kinase Activity
Protein Threonine Kinase Activity
Biological Process
G1/S Transition Of Mitotic Cell Cycle
Telomere Maintenance
Double-strand Break Repair Via Homologous Recombination
DNA Replication
Transcription-coupled Nucleotide-excision Repair
Base-excision Repair
Nucleotide-excision Repair
Nucleotide-excision Repair, Preincision Complex Stabilization
Nucleotide-excision Repair, Preincision Complex Assembly
Nucleotide-excision Repair, DNA Incision, 3'-to Lesion
Nucleotide-excision Repair, DNA Incision, 5'-to Lesion
Nucleotide-excision Repair, DNA Gap Filling
Mismatch Repair
Regulation Of Double-strand Break Repair Via Homologous Recombination
Translesion Synthesis
Mitotic G1 DNA Damage Checkpoint
Telomere Maintenance Via Semi-conservative Replication
Nucleotide-excision Repair, DNA Incision
Protein Localization To Chromosome
Interstrand Cross-link Repair
Error-prone Translesion Synthesis
DNA Damage Response, Detection Of DNA Damage
Error-free Translesion Synthesis
Regulation Of Cellular Response To Heat
Regulation Of Signal Transduction By P53 Class Mediator
Regulation Of DNA Damage Checkpoint
Negative Regulation Of Cell-matrix Adhesion
Protein Phosphorylation
Cell Adhesion
Neurotransmitter Secretion
Negative Regulation Of Keratinocyte Proliferation
GMP Metabolic Process
GDP Metabolic Process
Negative Regulation Of Wound Healing
Negative Regulation Of Cellular Response To Growth Factor Stimulus
Pathways
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Removal of the Flap Intermediate from the C-strand
Activation of ATR in response to replication stress
Regulation of HSF1-mediated heat shock response
HSF1 activation
Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Formation of Incision Complex in GG-NER
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Fanconi Anemia Pathway
Regulation of TP53 Activity through Phosphorylation
Activation of the pre-replicative complex
Removal of the Flap Intermediate
G2/M DNA damage checkpoint
Meiotic recombination
Dopamine Neurotransmitter Release Cycle
Syndecan interactions
Nephrin family interactions
Neurexins and neuroligins
Neurexins and neuroligins
Assembly and cell surface presentation of NMDA receptors
Drugs
Formic acid
Fostamatinib
Diseases
FG syndrome (FGS); Opitz-Kaveggia syndrome
GWAS
HDL cholesterol levels (
32203549
)
Platelet count (
32888494
)
Plateletcrit (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
63 interacting genes:
ACP5
AKAP9
APP
ATM
CALCOCO2
CASK
CCNC
CCNO
CDC5L
CDK1
CEP126
CFB
COPS6
CRMP1
DMRTB1
EEF1A1
EIF4G2
ERCC1
ERCC4
GAPDH
GOLM1
HERPUD1
HNRNPUL1
HUS1
LNX2
LRIF1
MARK2
MCM2
MCM5
MED1
MED31
MEN1
NDEL1
ORC1
ORC2
ORC4
ORC5
PCM1
PPP4C
PRC1
PRKCI
PRKDC
RAD1
RAD51
RAD52
RAD9A
RBM14
RBM48
RPA1
RPA3
RPLP1
SDF4
SERTAD3
SLC17A9
STAT3
TLE1
TUBB2A
UNC119
UNG
UTP14A
XPA
YWHAE
ZBTB14
88 interacting genes:
AKAP9
APBA1
ATP2B4
BNIP3L
C20orf85
CADM1
CASKIN1
CDK9
CNTNAP2
CNTNAP4
DDX54
DLG1
DLG4
DNAJC5
DUSP3
ELL2
EPB41
EPS8
ERBIN
F11R
FCHSD2
FMR1
GCNT3
GLS2
GRIK2
GRIN2A
GTSE1
HGS
ID1
IL15RA
IL18
KCNA4
KCNJ12
KCNJ2
KCNJ4
KIF2A
KLC4
LIN7A
LIN7B
MAPRE1
MAPRE2
MARK2
MARS1
MED1
MLLT6
MLX
NDEL1
NPHS1
NRXN1
NRXN2
NRXN3
NTN4
P2RX7
PARD3B
PARD6G
PCBP2
PCM1
PKP2
PLK2
PPP4R3A
PRC1
PRKCI
PRKD2
PRKN
PRPF3
PTGS2
RAB3A
RBBP6
RBM10
RBM14
RBM5
RPA2
RPH3A
SDC1
SDC2
SDC3
SDC4
SF3B2
SH2D4A
SLAIN2
SRPK2
TANC1
TBR1
TRIM22
TSPYL2
WHRN
WNT7B
YWHAE
Entrez ID
6118
8573
HPRD ID
01566
02164
Ensembl ID
ENSG00000117748
ENSG00000147044
Uniprot IDs
B4DUL2
P15927
A0A2R8Y6F8
A0A2R8YE77
O14936
PDB IDs
1DPU
1L1O
1QUQ
1Z1D
2PI2
2PQA
2Z6K
3KDF
4MQV
4OU0
1KGD
1KWA
1ZL8
3C0G
3C0H
3C0I
3MFR
3MFS
3MFT
3MFU
3TAC
6KMH
Enriched GO Terms of Interacting Partners
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