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CRMP1 and PSMD11
Data Source:
BioGRID
(two hybrid)
HPRD
(two hybrid)
CRMP1
PSMD11
Description
collapsin response mediator protein 1
proteasome 26S subunit, non-ATPase 11
Image
GO Annotations
Cellular Component
Nucleus
Centrosome
Spindle
Cytosol
Growth Cone
Midbody
Perikaryon
Proteasome Complex
Extracellular Region
Nucleus
Nucleoplasm
Cytosol
Proteasome Regulatory Particle, Lid Subcomplex
Membrane
Proteasome Accessory Complex
Secretory Granule Lumen
Ficolin-1-rich Granule Lumen
Molecular Function
Dihydropyrimidinase Activity
Protein Binding
Filamin Binding
Identical Protein Binding
Structural Molecule Activity
Protein Binding
Biological Process
Microtubule Cytoskeleton Organization
Nucleobase-containing Compound Metabolic Process
Pyrimidine Nucleobase Catabolic Process
Nervous System Development
Axon Guidance
Negative Regulation Of Neuron Projection Development
Negative Regulation Of Actin Filament Binding
MAPK Cascade
Protein Polyubiquitination
Stimulatory C-type Lectin Receptor Signaling Pathway
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent
Ubiquitin-dependent Protein Catabolic Process
Regulation Of Cellular Amino Acid Metabolic Process
Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle
Protein Deubiquitination
Anaphase-promoting Complex-dependent Catabolic Process
SCF-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tumor Necrosis Factor-mediated Signaling Pathway
NIK/NF-kappaB Signaling
Fc-epsilon Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasome Assembly
Neutrophil Degranulation
Regulation Of MRNA Stability
Post-translational Protein Modification
Stem Cell Differentiation
T Cell Receptor Signaling Pathway
Transmembrane Transport
Wnt Signaling Pathway, Planar Cell Polarity Pathway
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Interleukin-1-mediated Signaling Pathway
Negative Regulation Of Canonical Wnt Signaling Pathway
Positive Regulation Of Canonical Wnt Signaling Pathway
Regulation Of Mitotic Cell Cycle Phase Transition
Regulation Of Hematopoietic Stem Cell Differentiation
Pathways
CRMPs in Sema3A signaling
Activation of NF-kappaB in B cells
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
ER-Phagosome pathway
Cross-presentation of soluble exogenous antigens (endosomes)
Autodegradation of Cdh1 by Cdh1:APC/C
SCF-beta-TrCP mediated degradation of Emi1
APC/C:Cdc20 mediated degradation of Securin
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
Vpu mediated degradation of CD4
Vif-mediated degradation of APOBEC3G
SCF(Skp2)-mediated degradation of p27/p21
Degradation of beta-catenin by the destruction complex
Downstream TCR signaling
Regulation of activated PAK-2p34 by proteasome mediated degradation
Separation of Sister Chromatids
FCERI mediated NF-kB activation
Autodegradation of the E3 ubiquitin ligase COP1
Regulation of ornithine decarboxylase (ODC)
ABC-family proteins mediated transport
AUF1 (hnRNP D0) binds and destabilizes mRNA
Asymmetric localization of PCP proteins
Degradation of AXIN
Degradation of DVL
Hedgehog ligand biogenesis
Hh mutants are degraded by ERAD
Dectin-1 mediated noncanonical NF-kB signaling
CLEC7A (Dectin-1) signaling
Degradation of GLI1 by the proteasome
Degradation of GLI2 by the proteasome
GLI3 is processed to GLI3R by the proteasome
Hedgehog 'on' state
Regulation of RAS by GAPs
TNFR2 non-canonical NF-kB pathway
NIK-->noncanonical NF-kB signaling
Defective CFTR causes cystic fibrosis
MAPK6/MAPK4 signaling
UCH proteinases
Ub-specific processing proteases
Neutrophil degranulation
CDT1 association with the CDC6:ORC:origin complex
Orc1 removal from chromatin
CDK-mediated phosphorylation and removal of Cdc6
G2/M Checkpoints
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
Ubiquitin-dependent degradation of Cyclin D
The role of GTSE1 in G2/M progression after G2 checkpoint
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Regulation of RUNX2 expression and activity
Regulation of RUNX2 expression and activity
Regulation of RUNX3 expression and activity
Regulation of PTEN stability and activity
Neddylation
Regulation of expression of SLITs and ROBOs
Interleukin-1 signaling
Negative regulation of NOTCH4 signaling
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Blood trace element (Zn levels) (
23720494
)
Brain morphology (min-P) (
32665545
)
Brain morphology (MOSTest) (
32665545
)
Cortical surface area (MOSTest) (
32665545
)
Metabolite levels (
23823483
)
Subcortical volume (MOSTest) (
32665545
)
Interacting Genes
80 interacting genes:
AGR2
ALDH2
AMFR
ANXA7
AP3M1
ARL15
AXIN1
BID
BTBD2
CACNA1A
CCDC106
CCL18
CCT7
CDK5RAP2
CDK5RAP3
DDX18
DNAJB11
DPYSL2
DPYSL3
DUSP4
EEF1D
EIF2S2
EPN1
EXOSC8
FAS
FTH1
FUBP1
FXR1
GNE
GOLGA2
HDHD2
HGS
HMGB1
HNRNPH1
HNRNPH3
HNRNPUL1
HSPE1
HTT
IL33
KLHL20
LRRC1
LRRK2
LSM2
MAP3K20
MAPK8IP2
MCM3AP
MOB4
MRPS12
NAT9
NDUFV2
NVL
PAFAH1B3
PFN1
PLA2G2A
PMF1
PPP1R8
PSMD11
RACK1
RGL2
RGS2
ROCK1
RPA2
RPS6KA5
RTN4
SAT1
SEPHS1
SERPINB9
SNRPG
SPRY2
SRC
TFG
TK1
TRIP13
TSC22D1
UBE2A
UBE2B
VCP
VIM
YAE1
ZNF24
40 interacting genes:
APP
BRD7
CCDC90B
CCSER2
CDC42
COPS2
COPS6
CRMP1
EEF1A1
EEF1G
GAPDH
GDF9
HAP1
IGSF21
LRIF1
MED31
NFKB2
PRKAA1
PRKAB2
PRKACA
PRMT6
PSMC5
PSMD6
PTN
PTPRK
RBM48
SETDB1
SMAD1
SMAD2
SMAD3
SMAD4
SMAD5
TLE1
TP53
TUBB2A
UBC
UNC119
USP4
ZBTB16
ZHX1
Entrez ID
1400
5717
HPRD ID
03913
05119
Ensembl ID
ENSG00000072832
ENSG00000108671
Uniprot IDs
B3KT07
B3KV96
E9PD68
Q14194
Q96I11
X5DNI1
O00231
PDB IDs
4B3Z
5GJQ
5GJR
5L4K
5LN3
5M32
5T0C
5T0G
5T0H
5T0I
5T0J
5VFP
5VFQ
5VFR
5VFS
5VFT
5VFU
5VGZ
5VHF
5VHH
5VHI
5VHS
6MSB
6MSD
6MSE
6MSG
6MSH
6MSJ
6MSK
6WJD
6WJN
Enriched GO Terms of Interacting Partners
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