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ACTA1 and TRIM55
Data Source:
BioGRID
(two hybrid)
ACTA1
TRIM55
Description
actin alpha 1, skeletal muscle
tripartite motif containing 55
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytosol
Striated Muscle Thin Filament
Dynactin Complex
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Nucleus
Cytoplasm
Microtubule
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Myosin Binding
ADP Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Biological Process
Muscle Contraction
Response To Mechanical Stimulus
Response To Extracellular Stimulus
Response To Lithium Ion
Positive Regulation Of Gene Expression
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Adaptation
Response To Steroid Hormone
Skeletal Muscle Fiber Development
Cellular Response To Organonitrogen Compound
Mesenchyme Migration
Leukocyte Migration Involved In Inflammatory Response
Signal Transduction
Protein Ubiquitination
Diapedesis
Macrophage Migration
Pathways
Striated Muscle Contraction
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Diseases
Congenital fiber type disproportion (CFTD)
Cap myopathy
Nemaline myopathy
GWAS
Coronary heart disease event reduction (statin therapy interaction) (
22666496
)
Metabolite levels (
23823483
)
Recurrent major depressive disorder (
29317602
)
Interacting Genes
114 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
310 interacting genes:
ACBD4
ACD
ACTA1
ADAMTSL4
AEBP2
AFM
AGO2
AKR1C8P
ALKBH3
ANKRD1
ANKRD39
APLN
APOBEC4
ARL6IP4
ATG4D
ATP5F1B
ATP5F1D
ATXN3
ATXN3L
ATXN7L1
BCAT1
BCHE
BRAP
BRD4
BRWD1
BTBD9
BYSL
C10orf88
C12orf4
C1orf35
C3orf36
C8orf74
CADPS
CAMK2A
CAPN3
CARS1
CBX2
CCDC120
CCDC130
CCDC28B
CDK3
CDS2
CENPK
CHMP7
CKM
COA7
COX4I1
CRCT1
CTAG1A
CTAG1B
CTNNB1
CTSF
CYB5R2
CYP46A1
CYTOR
DAPL1
DCAF11
DCAF6
DCTN3
DECR2
DEF8
DEK
DES
DNTTIP1
DOCK7
DYNLT2B
EED
EEF1G
EHHADH
EIF3E
ELAPOR1
EPS8L2
ESPL1
EZH2
FAM185A
FAM90A1
FANK1
FASTKD1
FHL2
FKBP6
FLNA
FLNB
FLNC
FRMD6
FYN
GABPB1
GATA3
GFM1
GLI4
GMEB1
GOLGA2P5
GPRIN2
GPS1
GRB10
GRB14
HID1
HIRA
HOXA1
HROB
HSPB1
ID1
IFI35
IGF2
IK
IL37
ILF3
INCA1
ING4
INKA1
IQUB
IRF2
IRF3
ITGB5
JADE3
KBTBD4
KCTD15
KIAA0087
KIAA0408
KIF13A
KIF1B
KIF5A
KLHDC4
KLHL36
KMT2B
KYAT1
LAGE3
LAMTOR5
LAPTM4A
LIMS2
LINC00518
LINC00663
LINC00905
LINC01588
LMCD1
LMO2
LRRC56
LYN
LYNX1
MAGEC3
MALSU1
MAP3K14
MBD4
MBIP
MCM7
MDM4
MIDN
MIIP
MKI67
MLH3
MLLT11
MPP1
MPZL1
MRPL19
MRPL20-AS1
MRPL41
MSRB3
MYBPC1
MYBPC3
MYBPHL
MYC
MYCT1
MYOT
MYOZ1
NDUFA1
NDUFA8
NEB
NEBL
NEFL
NGEF
NOMO1
NR1D2
NR2C2
NSD3
NSUN7
NUFIP2
ODF2
OGFOD2
OTUB1
OTUB2
P3H3
PACRGL
PAFAH1B2
PCGF1
PCGF3
PCGF6
PELI3
PELO
PHC2
PHF23
PIAS1
PIAS2
PIAS3
PIP4K2B
PKM
PLEKHG4
PLXNA3
POLD1
POLR2E
PPARA
PPIE
PRKAB2
PRKACA
PRR30
PRRT1
PYGM
RABEPK
RAD23A
RAI2
RBM14
RELA
REX1BD
RGR
RHEB
RHPN1
RING1
RNF10
RNF114
RPS4X
RRAS
RUSC1
RUSC1-AS1
SEC23B
SET
SHFL
SLC6A13
SLFN12
SNW1
SPATS1
SPRYD7
SPSB1
SPSB2
SQSTM1
STAM
SYMPK
SYNCRIP
TCAP
TCP10L
TEX19
THAP3
TIGD5
TIMM17B
TMBIM1
TMEM35A
TNIP3
TNNI1
TNNI2
TNNI3
TOR1AIP2
TPD52L3
TRAF3IP2
TRIB3
TRIM23
TRIM27
TRIM35
TRIM41
TRIM54
TRIM63
TRIM69
TRMT10B
TSC2
TSC22D4
TTN
TUBGCP4
UBA3
UBE2D1
UBE2D2
UBE2D3
UBE2E3
UBE2L3
UCHL3
UCHL5
UNKL
USP13
USP28
USP4
USP5
USP7
USP8
UXT
VAC14
VPS37A
WT1
XAGE1B
YOD1
YPEL3
ZBTB14
ZBTB17
ZC2HC1C
ZC3H12A
ZC3HC1
ZFYVE19
ZNF124
ZNF20
ZNF302
ZNF333
ZNF345
ZNF431
ZNF436
ZNF460
ZNF566
ZNF57
ZNF581
ZNF597
ZNF649
ZNF653
ZNF667-AS1
ZNF767P
ZNF775
ZNF83
ZSCAN16
Entrez ID
58
84675
HPRD ID
00030
05927
Ensembl ID
ENSG00000143632
ENSG00000147573
Uniprot IDs
P68133
Q9BYV6
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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