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TRIM55 and LMO2
Data Source:
BioGRID
(two hybrid)
TRIM55
LMO2
Description
tripartite motif containing 55
LIM domain only 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Microtubule
Nucleoplasm
Transcription Regulator Complex
Molecular Function
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
RNA Polymerase II Activating Transcription Factor Binding
Transcription Coregulator Binding
Transcription Coactivator Activity
Protein Binding
BHLH Transcription Factor Binding
Metal Ion Binding
Biological Process
Leukocyte Migration Involved In Inflammatory Response
Signal Transduction
Protein Ubiquitination
Diapedesis
Macrophage Migration
Multicellular Organism Development
Positive Regulation Of Transcription By RNA Polymerase II
Cellular Response To Thyroid Hormone Stimulus
Regulation Of Hematopoietic Stem Cell Differentiation
Pathways
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Drugs
Diseases
Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS
Coronary heart disease event reduction (statin therapy interaction) (
22666496
)
Metabolite levels (
23823483
)
Recurrent major depressive disorder (
29317602
)
Cognitive performance (
19734545
)
Eosinophil counts (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Iron status biomarkers (transferrin saturation) (
28334935
)
Mean corpuscular hemoglobin (
32888494
27863252
)
Mean corpuscular volume (
32888494
27863252
)
Mean reticulocyte volume (
32888494
)
Mean spheric corpuscular volume (
32888494
)
Red blood cell count (
32888494
27863252
)
Interacting Genes
310 interacting genes:
ACBD4
ACD
ACTA1
ADAMTSL4
AEBP2
AFM
AGO2
AKR1C8P
ALKBH3
ANKRD1
ANKRD39
APLN
APOBEC4
ARL6IP4
ATG4D
ATP5F1B
ATP5F1D
ATXN3
ATXN3L
ATXN7L1
BCAT1
BCHE
BRAP
BRD4
BRWD1
BTBD9
BYSL
C10orf88
C12orf4
C1orf35
C3orf36
C8orf74
CADPS
CAMK2A
CAPN3
CARS1
CBX2
CCDC120
CCDC130
CCDC28B
CDK3
CDS2
CENPK
CHMP7
CKM
COA7
COX4I1
CRCT1
CTAG1A
CTAG1B
CTNNB1
CTSF
CYB5R2
CYP46A1
CYTOR
DAPL1
DCAF11
DCAF6
DCTN3
DECR2
DEF8
DEK
DES
DNTTIP1
DOCK7
DYNLT2B
EED
EEF1G
EHHADH
EIF3E
ELAPOR1
EPS8L2
ESPL1
EZH2
FAM185A
FAM90A1
FANK1
FASTKD1
FHL2
FKBP6
FLNA
FLNB
FLNC
FRMD6
FYN
GABPB1
GATA3
GFM1
GLI4
GMEB1
GOLGA2P5
GPRIN2
GPS1
GRB10
GRB14
HID1
HIRA
HOXA1
HROB
HSPB1
ID1
IFI35
IGF2
IK
IL37
ILF3
INCA1
ING4
INKA1
IQUB
IRF2
IRF3
ITGB5
JADE3
KBTBD4
KCTD15
KIAA0087
KIAA0408
KIF13A
KIF1B
KIF5A
KLHDC4
KLHL36
KMT2B
KYAT1
LAGE3
LAMTOR5
LAPTM4A
LIMS2
LINC00518
LINC00663
LINC00905
LINC01588
LMCD1
LMO2
LRRC56
LYN
LYNX1
MAGEC3
MALSU1
MAP3K14
MBD4
MBIP
MCM7
MDM4
MIDN
MIIP
MKI67
MLH3
MLLT11
MPP1
MPZL1
MRPL19
MRPL20-AS1
MRPL41
MSRB3
MYBPC1
MYBPC3
MYBPHL
MYC
MYCT1
MYOT
MYOZ1
NDUFA1
NDUFA8
NEB
NEBL
NEFL
NGEF
NOMO1
NR1D2
NR2C2
NSD3
NSUN7
NUFIP2
ODF2
OGFOD2
OTUB1
OTUB2
P3H3
PACRGL
PAFAH1B2
PCGF1
PCGF3
PCGF6
PELI3
PELO
PHC2
PHF23
PIAS1
PIAS2
PIAS3
PIP4K2B
PKM
PLEKHG4
PLXNA3
POLD1
POLR2E
PPARA
PPIE
PRKAB2
PRKACA
PRR30
PRRT1
PYGM
RABEPK
RAD23A
RAI2
RBM14
RELA
REX1BD
RGR
RHEB
RHPN1
RING1
RNF10
RNF114
RPS4X
RRAS
RUSC1
RUSC1-AS1
SEC23B
SET
SHFL
SLC6A13
SLFN12
SNW1
SPATS1
SPRYD7
SPSB1
SPSB2
SQSTM1
STAM
SYMPK
SYNCRIP
TCAP
TCP10L
TEX19
THAP3
TIGD5
TIMM17B
TMBIM1
TMEM35A
TNIP3
TNNI1
TNNI2
TNNI3
TOR1AIP2
TPD52L3
TRAF3IP2
TRIB3
TRIM23
TRIM27
TRIM35
TRIM41
TRIM54
TRIM63
TRIM69
TRMT10B
TSC2
TSC22D4
TTN
TUBGCP4
UBA3
UBE2D1
UBE2D2
UBE2D3
UBE2E3
UBE2L3
UCHL3
UCHL5
UNKL
USP13
USP28
USP4
USP5
USP7
USP8
UXT
VAC14
VPS37A
WT1
XAGE1B
YOD1
YPEL3
ZBTB14
ZBTB17
ZC2HC1C
ZC3H12A
ZC3HC1
ZFYVE19
ZNF124
ZNF20
ZNF302
ZNF333
ZNF345
ZNF431
ZNF436
ZNF460
ZNF566
ZNF57
ZNF581
ZNF597
ZNF649
ZNF653
ZNF667-AS1
ZNF767P
ZNF775
ZNF83
ZSCAN16
188 interacting genes:
ABI2
ADAMTSL4
AFDN
AGTRAP
AIMP2
ALDH6A1
ARHGEF5
ARID5A
ARNT2
AXIN1
BANP
BCAS2
BEX2
BLZF1
BYSL
C1orf109
C1orf94
CALCOCO2
CBY2
CCDC33
CDC25A
CDC5L
CDX4
CLHC1
CMTM5
CORO1A
CORO1C
DAZAP2
DBF4B
DDIT3
DMRT3
DRAP1
DYDC1
EFHC1
EFHC2
EHMT2
EIF3B
EIF4EBP1
ELF2
ENKD1
ERBIN
FAAP20
FAM214B
FAM228A
FAM90A1
FHL3
FHL5
GAS8
GATA1
GATA2
GATA3
GFAP
GMEB2
GOLGA2
GRB2
HDAC5
HNRNPC
HNRNPM
HOOK1
ICA1L
IFT43
IHO1
IKZF1
IKZF3
INCA1
ISL1
ISY1
KANK2
KAZN
KDM5A
KIF2A
KIF3B
KPRP
KRT15
KRT34
KRT40
KRT75
KRT80
KRTAP10-7
LDB1
LDB2
LDOC1
LMO4
LMOD3
LYL1
LZTS1
LZTS2
MAGEA8
MAPRE1
MAPRE2
MAPRE3
MBIP
MISP
MRFAP1L1
MSN
MTUS2
MYOZ3
N4BP2L2
NCAPH2
NDOR1
NDUFAB1
NDUFB7
NFKBID
NHLH1
NIF3L1
NOTCH2NLA
NOXA1
NSMF
NTAQ1
NUP62
NUTM1
PATZ1
PAX9
PBX4
PDE9A
PHC2
POLR2G
PPP1R32
PRDM6
PRKG1
PSMA1
RBBP8
RCN1
REL
RELA
RINT1
RLIM
ROCK1
RTL8C
RUSC1
SAXO1
SGTB
SKP1
SMAD2
SMUG1
SNAPC5
SOX5
SP1
SSX2IP
STAT1
STAT3
STIP1
TAL1
TAL2
TBX2
TCP10L
TEKT3
TFIP11
TFPT
THAP6
TLE5
TLX3
TRIB3
TRIM23
TRIM54
TRIM55
TRIM63
TRIP6
TSC1
TSC22D4
TSEN15
TSEN54
TSGA10IP
TSPYL2
TSSK3
TUFT1
UBA6
UBASH3B
UBE2I
USH1G
VBP1
VEZF1
VMAC
WASF1
WASHC1
YOD1
YPEL3
ZFP64
ZMYND12
ZNF185
ZNF19
ZNF24
ZNF250
ZNF34
ZNF410
ZNF641
ZNF655
ZNF688
Entrez ID
84675
4005
HPRD ID
05927
01586
Ensembl ID
ENSG00000147573
ENSG00000135363
Uniprot IDs
Q9BYV6
P25791
PDB IDs
2XJY
2XJZ
2YPA
4KFZ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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