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ACTA1 and LASP1
Data Source:
HPRD
(in vitro)
ACTA1
LASP1
Description
actin alpha 1, skeletal muscle
LIM and SH3 protein 1
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytosol
Striated Muscle Thin Filament
Dynactin Complex
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Cytoplasm
Focal Adhesion
Cortical Actin Cytoskeleton
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Myosin Binding
ADP Binding
Protein Binding
Ion Transmembrane Transporter Activity
Cadherin Binding
Metal Ion Binding
Actin Filament Binding
Biological Process
Muscle Contraction
Response To Mechanical Stimulus
Response To Extracellular Stimulus
Response To Lithium Ion
Positive Regulation Of Gene Expression
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Adaptation
Response To Steroid Hormone
Skeletal Muscle Fiber Development
Cellular Response To Organonitrogen Compound
Mesenchyme Migration
Ion Transport
Ion Transmembrane Transport
Pathways
Striated Muscle Contraction
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Diseases
Congenital fiber type disproportion (CFTD)
Cap myopathy
Nemaline myopathy
GWAS
Cognitive decline rate in late mild cognitive impairment (
26252872
)
Peginterferon alfa-2a treatment response in chronic hepatitis B infection (
30972912
)
Interacting Genes
114 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
121 interacting genes:
ACD
ACTA1
ACTB
ACTC1
ANKS1A
ARHGEF15
ARHGEF16
ARID5A
ATXN1
BAG4
BAHD1
BHLHE40
C14orf119
C19orf54
CAMK2A
CATSPER1
CDK7
CERCAM
CHERP
COPS5
CRK
CRYBA1
CRYBA2
CSTF2T
CTNNA3
CYSRT1
DAZAP2
DMRT3
DNMT1
DOK6
DTX2
EHMT2
EVX2
FAM168A
FAM168B
FBXO17
FHL3
FOXH1
FXR2
GAS8
GCM2
GOLGA2
GUCD1
HGS
HNRNPF
HOXA1
INTS11
KRTAP10-8
KRTAP12-4
KRTAP19-3
KRTAP19-4
KRTAP19-6
KRTAP26-1
KRTAP3-2
KRTAP3-3
KRTAP4-2
KRTAP6-2
LENG8
LMO4
LZTS2
MDFI
MED25
MGAT5B
MKRN3
NOXA1
NUTF2
OTX1
OXER1
PITX1
PLSCR1
POLD1
POT1
POU1F1
PPP1R32
PRKAR2B
PRKG1
PRKG2
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PRR35
PSMA3
QRICH1
RBFOX1
RBPMS
RBPMS2
REL
RHOXF2
RNF38
SEPTIN3
SPAG8
SPRY2
STAT3
TCF4
TEKT3
TEKT4
TEKT5
TERF1
TFG
THAP1
TINF2
TLX3
TNS2
TRIM27
TRIP13
UBQLN2
UFSP1
UHRF1
VAC14
VEZF1
VGLL3
VPS37C
WWOX
YES1
YTHDF1
ZBTB9
ZC2HC1A
ZC3H10
ZYX
Entrez ID
58
3927
HPRD ID
00030
04229
Ensembl ID
ENSG00000143632
ENSG00000002834
Uniprot IDs
P68133
A0A024R1S8
B4DIC4
Q14847
PDB IDs
3I35
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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