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ACTA1 and ANXA2
Data Source:
BioGRID
(two hybrid)
ACTA1
ANXA2
Description
actin alpha 1, skeletal muscle
annexin A2
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytosol
Striated Muscle Thin Filament
Dynactin Complex
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Extracellular Region
Basement Membrane
Extracellular Space
Nucleus
Cytoplasm
Lysosomal Membrane
Endosome
Lipid Droplet
Plasma Membrane
Adherens Junction
Cell Surface
Membrane
Basolateral Plasma Membrane
Midbody
Late Endosome Membrane
Vesicle
Azurophil Granule Lumen
Melanosome
Membrane Raft
Collagen-containing Extracellular Matrix
Extracellular Exosome
AnxA2-p11 Complex
PCSK9-AnxA2 Complex
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Myosin Binding
ADP Binding
Phosphatidylserine Binding
Protease Binding
RNA Binding
Serine-type Endopeptidase Inhibitor Activity
Calcium Channel Activity
Calcium Ion Binding
Protein Binding
Calcium-dependent Phospholipid Binding
Phosphatidylinositol-4,5-bisphosphate Binding
Cytoskeletal Protein Binding
Phospholipase A2 Inhibitor Activity
Identical Protein Binding
S100 Protein Binding
Virion Binding
Calcium-dependent Protein Binding
Cadherin Binding Involved In Cell-cell Adhesion
Biological Process
Muscle Contraction
Response To Mechanical Stimulus
Response To Extracellular Stimulus
Response To Lithium Ion
Positive Regulation Of Gene Expression
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Adaptation
Response To Steroid Hormone
Skeletal Muscle Fiber Development
Cellular Response To Organonitrogen Compound
Mesenchyme Migration
Angiogenesis
Membrane Raft Assembly
Positive Regulation Of Receptor Recycling
Vesicle Budding From Membrane
Negative Regulation Of Endopeptidase Activity
Viral Process
Positive Regulation Of Vesicle Fusion
Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process
Interleukin-12-mediated Signaling Pathway
Osteoclast Development
Neutrophil Degranulation
Positive Regulation Of Vacuole Organization
Negative Regulation Of Development Of Symbiont Involved In Interaction With Host
Catabolism By Host Of Symbiont Protein
Negative Regulation By Host Of Symbiont Molecular Function
Calcium Ion Transmembrane Transport
Cell-cell Adhesion
Positive Regulation Of Low-density Lipoprotein Particle Clearance
Positive Regulation Of Low-density Lipoprotein Particle Receptor Binding
Positive Regulation Of Low-density Lipoprotein Receptor Activity
Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport
Pathways
Striated Muscle Contraction
Smooth Muscle Contraction
Neutrophil degranulation
Dissolution of Fibrin Clot
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Tenecteplase
Fluocinolone acetonide
Lanoteplase
Artenimol
Diseases
Congenital fiber type disproportion (CFTD)
Cap myopathy
Nemaline myopathy
GWAS
Asthma (
31959851
)
Asthma (age of onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Blood protein levels (
30072576
28240269
)
Night sleep phenotypes (
27126917
)
Type 2 diabetes (
25102180
)
Interacting Genes
114 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
44 interacting genes:
ACTA1
APOH
APP
CCDC32
CD99
CDC42
CEACAM1
CTSB
CTSS
DYSF
GRB2
HMGA1
LGALS13
LINC01554
LYPLA1
MAP3K4
MYOC
NOD2
OGDH
PHB
PLA1A
PLA2G4A
PLAT
PLG
POT1
PRKCA
PRKCB
PTEN
RPS2
S100A10
S100A4
S100A6
SMN1
SNX17
SOS1
SRC
STAT6
TENT2
TERF1
TERT
TP53
TRPV5
YWHAQ
ZBTB4
Entrez ID
58
302
HPRD ID
00030
01061
Ensembl ID
ENSG00000143632
ENSG00000182718
Uniprot IDs
P68133
A0A024R5Z7
P07355
PDB IDs
1W7B
1XJL
2HYU
2HYV
2HYW
4DRW
4FTG
4HRH
5LPU
5LPX
5LQ0
5LQ2
5N7D
5N7F
5N7G
6TWQ
6TWU
6TWX
6TWY
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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