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ACTA1 and KIF23
Data Source:
HPRD
(in vitro)
ACTA1
KIF23
Description
actin alpha 1, skeletal muscle
kinesin family member 23
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytosol
Striated Muscle Thin Filament
Dynactin Complex
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Nucleus
Nucleoplasm
Centrosome
Spindle
Cytosol
Kinesin Complex
Microtubule
Focal Adhesion
Midbody
Mitotic Spindle
Flemming Body
Centralspindlin Complex
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Myosin Binding
ADP Binding
Microtubule Motor Activity
Protein Binding
ATP Binding
Microtubule Binding
ATPase Activity
Biological Process
Muscle Contraction
Response To Mechanical Stimulus
Response To Extracellular Stimulus
Response To Lithium Ion
Positive Regulation Of Gene Expression
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Adaptation
Response To Steroid Hormone
Skeletal Muscle Fiber Development
Cellular Response To Organonitrogen Compound
Mesenchyme Migration
Mitotic Spindle Elongation
Mitotic Cytokinesis
Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum
Microtubule-based Movement
Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II
Positive Regulation Of Cytokinesis
Mitotic Spindle Midzone Assembly
Pathways
Striated Muscle Contraction
MHC class II antigen presentation
COPI-dependent Golgi-to-ER retrograde traffic
Mitotic Telophase/Cytokinesis
Kinesins
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Diseases
Congenital fiber type disproportion (CFTD)
Cap myopathy
Nemaline myopathy
GWAS
Mean reticulocyte volume (
32888494
)
Rheumatoid arthritis (ACPA-positive) (
24532676
)
Interacting Genes
114 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
13 interacting genes:
ACTA1
ARF3
CLK1
LATS2
PLK1
PPP1CB
RACGAP1
RBM34
SUMO2
USP8
YWHAB
YWHAG
YWHAQ
Entrez ID
58
9493
HPRD ID
00030
05455
Ensembl ID
ENSG00000143632
ENSG00000137807
Uniprot IDs
P68133
Q02241
PDB IDs
3VHX
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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