Wiki-MPM
About
Search
Browse
People
Funding
Updates
Search
ACTA1 and MYO6
Data Source:
HPRD
(in vitro)
ACTA1
MYO6
Description
actin alpha 1, skeletal muscle
myosin VI
Image
No pdb structure
GO Annotations
Cellular Component
Stress Fiber
Extracellular Space
Cytosol
Striated Muscle Thin Filament
Dynactin Complex
Actin Filament
Actin Cytoskeleton
Sarcomere
Lamellipodium
Filopodium
Cell Body
Extracellular Exosome
Blood Microparticle
Ruffle
Nucleus
Nucleoplasm
Cytoplasm
Lysosomal Membrane
Golgi Apparatus
Cytosol
Actin Filament
Plasma Membrane
Microvillus
Clathrin-coated Pit
Cell Cortex
Actin Cytoskeleton
Membrane
Unconventional Myosin Complex
RNA Polymerase II, Holoenzyme
Endocytic Vesicle
Filopodium
Clathrin-coated Vesicle Membrane
Cytoplasmic Vesicle
Filamentous Actin
Nuclear Membrane
Vesicle
Ruffle Membrane
Clathrin-coated Endocytic Vesicle
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Structural Constituent Of Cytoskeleton
Protein Binding
ATP Binding
Myosin Binding
ADP Binding
Microfilament Motor Activity
Motor Activity
Actin Binding
Protein Binding
Calmodulin Binding
ATP Binding
Actin-dependent ATPase Activity
ADP Binding
Actin Filament Binding
Minus-end Directed Microfilament Motor Activity
Biological Process
Muscle Contraction
Response To Mechanical Stimulus
Response To Extracellular Stimulus
Response To Lithium Ion
Positive Regulation Of Gene Expression
Muscle Filament Sliding
Skeletal Muscle Thin Filament Assembly
Skeletal Muscle Fiber Adaptation
Response To Steroid Hormone
Skeletal Muscle Fiber Development
Cellular Response To Organonitrogen Compound
Mesenchyme Migration
Intracellular Protein Transport
Endocytosis
Actin Filament Organization
Sensory Perception Of Sound
Actin Filament-based Movement
Vesicle Transport Along Actin Filament
DNA Damage Response, Signal Transduction By P53 Class Mediator
Inner Ear Morphogenesis
Inner Ear Auditory Receptor Cell Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Secretion
Pathways
Striated Muscle Contraction
Gap junction degradation
Trafficking of AMPA receptors
Drugs
Latrunculin A
Sucrose
Ulapualide A
Kabiramide C
Jaspisamide A
Tmr
1-Methylhistidine
Phosphoaminophosphonic Acid-Adenylate Ester
Aplyronine A
Reidispongiolide A
Reidispongiolide C
Sphinxolide B
Latrunculin B
Diseases
Congenital fiber type disproportion (CFTD)
Cap myopathy
Nemaline myopathy
Deafness, autosomal dominant
Deafness, autosomal recessive
GWAS
Prostate cancer (
25217961
)
Systolic blood pressure x smoking status (ever vs never) interaction (2df test) (
29455858
)
Interacting Genes
114 interacting genes:
ABL1
ABRA
ACTR10
ACTR1B
ADSS2
AFAP1
AIF1
AJUBA
AMOT
ANXA2
BIN1
CCIN
CCT2
CCT4
CCT5
CFL1
CLIC5
CNN1
CORO2B
COTL1
CTNND1
CTTN
CYFIP1
CYTH1
DHX9
DLG1
DMD
DNASE1
DNMBP
DTNA
DUX4L9
EGFR
EPB41
EPB41L2
EPS8
FGD4
FHOD1
FSCN1
GAS2
GAS7
GC
GSN
HCLS1
HDAC4
HIP1R
HSPB2
HTRA2
IQGAP1
ITGA2
ITPKA
KIF23
KLHL20
LASP1
MACF1
MAP1A
MAPT
MIB2
MINPP1
MYL1
MYLK
MYO10
MYO6
MYO7A
MYO9B
NEXN
NR3C2
NRAP
PAK1
PARVA
PCYT1B
PFDN1
PFN1
PHACTR1
PLD1
PPP1R9B
PRKCA
PRKCD
PRKCE
RAC1
RNF167
RPS6KB1
S100A1
S100A4
SCIN
SMTN
SNCA
SORBS1
SPRR1A
SPTA1
SPTAN1
SPTBN2
TAGLN
TJP1
TLN1
TMSB4X
TMSB4Y
TNNI1
TNNI3
TNNI3K
TP53
TPM2
TPM3
TRIM55
TRIM63
TTN
UBC
USP25
USP6NL
UTRN
VASP
VAV1
VCL
VIL1
XIRP1
20 interacting genes:
ACTA1
APC
CALCOCO2
CALM2
CDC42
CDH1
CLTB
DAB1
DAB2
DLG1
GIPC1
LRCH3
OPTN
PAK1
PAK3
RNF11
TOM1
TOM1L2
UBC
WBP2
Entrez ID
58
4646
HPRD ID
00030
02985
Ensembl ID
ENSG00000143632
ENSG00000196586
Uniprot IDs
P68133
Q9UM54
PDB IDs
2N0Z
2N10
2N11
2N12
2N13
6E5N
6J56
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?