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TRIM54 and SPG21
Data Source:
BioGRID
(two hybrid, two hybrid)
TRIM54
SPG21
Description
tripartite motif containing 54
SPG21 abhydrolase domain containing, maspardin
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Microtubule
Microtubule Associated Complex
Z Disc
Golgi Apparatus
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Intracellular Membrane-bounded Organelle
Molecular Function
Protein Binding
Microtubule Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Protein Binding
CD4 Receptor Binding
Biological Process
Microtubule-based Process
Negative Regulation Of Microtubule Depolymerization
Signal Transduction
Multicellular Organism Development
Protein Ubiquitination
Cell Differentiation
Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases
Hereditary spastic paraplegia (SPG)
GWAS
Mean corpuscular hemoglobin (
32888494
)
Interacting Genes
317 interacting genes:
AAMDC
ABHD17C
ADCY4
AGFG1
AIFM2
AK2
AK3
ANKRD11
ANKRD45
ARFIP2
ARHGAP29
ARHGEF5
ARHGEF6
ARMC7
ATXN3
ATXN3L
ATXN7
BBX
BMF
BSCL2
BYSL
C14orf39
C1orf109
C1orf216
C1orf35
C1QTNF2
C2CD6
C2orf49
C8orf74
CALM3
CARD9
CAVIN2
CBX8
CCDC102B
CCDC146
CCDC17
CCDC26
CCDC28A
CCDC87
CCHCR1
CCNC
CDC37
CDK18
CDKAL1
CDKN1A
CENPX
CEP57L1
CEP68
CFAP100
CFAP206
CFAP53
CHCHD2
CHD2
CHD3
CKM
CLPP
CMIP
CNGA3
CRADD
CSNK2B
CTNNA3
CWF19L2
CYTH4
DAXX
DCAF8
DCLRE1B
DCUN1D1
DDX6
DEUP1
DNAL4
DNASE1L1
DPYSL4
DRG2
DTNB
DTX2
DUSP16
DVL3
DYNC2I2
DYNLL1
EHHADH
EIF4E2
ELMO1
ELOA
ENKD1
EPHB2
EPM2AIP1
EXOC7
EXOC8
EXOSC5
EXTL2
FAM110A
FAM124A
FAM124B
FAM161A
FAM50B
FAM90A1
FAM9A
FARS2
FBF1
FBXO16
FBXW2
FLNC
FMNL1
G2E3
GAS8
GEM
GIMAP2
GLP2R
GMCL1
GNG13
GNL3L
GTF2I
GTF2IRD2
GTF2IRD2B
HAUS1
HBG1
HDAC10
HGS
HMMR
HOXB5
HSF2
HSPB1
HYAL2
IL18RAP
IL36A
IL4I1
ING3
INPP5J
IQUB
ITGAE
ITPKB
JOSD1
KANK2
KAT14
KDM1A
KIF9
KIFC3
KLHL38
KLHL42
KPNA2
KRT1
KRT3
KRT4
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRT78
KRT79
KRT8
KRTAP11-1
KRTAP9-2
LENG1
LIN37
LINC00887
LMO1
LMO2
LMO3
LMO4
LNX1
LSM2
MAD2L2
MAOB
MAPK3
MBD3
MCM7
MEAF6
MFAP1
MGARP
MICAL2
MID2
MNS1
MRTFA
MSH5
MYLK2
MYO15B
MYO5B
NEK6
NGLY1
NTAQ1
NUP54
NUP58
OFCC1
OSGIN1
OSTF1
OTUB1
OTUB2
PABPC3
PAIP2
PARVG
PCDHGB1
PCDHGC3
PCSK7
PDZK1IP1
PICK1
PIK3R3
PIWIL1
PLEKHM1
PLK4
PPIG
PPP1R18
PRF1
PRKAB2
PRKG1
PRMT5
PRPF18
PRR35
PSMA1
PYGM
RAB35
RABGEF1
RAD23A
RAPSN
RASSF10
RBM15B
RBM41
RCOR3
RELT
RIMS3
RNF4
RSRC2
RUNX1T1
SCNM1
SDCBP
SEC14L4
SELE
SEMA4C
SENP3
SH2D1B
SHC3
SLC13A2
SLITRK3
SMARCD1
SMARCE1
SNF8
SOX14
SPG21
SPRING1
SSX2IP
STAM
STRC
STXBP4
STYXL1
SYCE3
SYTL5
TBC1D22B
TCAF1
TCAP
TCEA2
TCEANC
TCHP
TEAD4
TEPSIN
THAP4
THOC1
TJAP1
TLE6
TLR10
TMEM30A
TNFAIP1
TNR
TRIM55
TRIM63
TRIM69
TRIML2
TSG101
TSHZ3
TSPEAR
TSSK3
TTC23
TTC9C
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2N
UBE2U
UBE2V2
UBL4A
UCHL1
UCHL3
UCHL5
USHBP1
USP15
USP18
USP2
USP21
USP33
USP35
USP4
USP5
USP7
USP8
UTP14C
VAMP4
VCAM1
VCP
VPS28
VPS9D1
XAF1
YEATS4
YOD1
ZBTB16
ZFHX3
ZGPAT
ZNF180
ZNF182
ZNF250
ZNF267
ZNF366
ZNF417
ZNF572
ZNF587
ZNF667-AS1
164 interacting genes:
ACOT13
AGTR1
AGTRAP
AKIRIN2
APOC1
ARL6IP1
ARL8A
ARMC12
ARMC7
ATP5ME
ATPAF2
BORCS6
BSND
C10orf82
C9orf24
CCDC102B
CCDC153
CCDC33
CCHCR1
CD4
CDK2AP1
CDKN2B
CEP76
CEPT1
CFAP410
CIDEB
CLDN22
CMTM4
CMTM5
CMTM6
COG3
COG6
CPSF7
CRX
CRYAA
CRYAA2
CT55
CTIF
CTPS2
CUTC
DCTPP1
DTX2
DTX3L
EFHC2
EIF1B
EIF4H
EYA2
FAM114A1
FAM86C1P
FBXO44
FLACC1
GAD2
GAS8
GEMIN2
GEMIN4
GGA2
GOLGA2
GOLT1B
GRPEL1
GSK3A
HNRNPH1
HPRT1
HSD17B13
IKZF3
INCA1
IQCB1
KCTD9
KRT13
KRT15
KRT19
KRT31
LEPROTL1
LMNA
LMO1
LNX1
LSMEM2
MAB21L3
MID2
MPC2
MTMR9
MTUS2
MYG1
MYOG
N4BP3
NAB2
NDUFAF2
NIF3L1
NME4
NQO2
NR1D1
NRDE2
NUP54
PAX6
PBX4
PCBD2
PCNA
PDE5A
PEF1
PFDN5
PLP2
PNMA5
PPM1J
PRPS1
PRTFDC1
PSMB4
PTPA
RABAC1
RAD51C
REEP6
REL
ROPN1
RPRD1B
RPS19
RTL8B
RTN4
S100B
SATB1
SCAMP1
SEPTIN5
SFT2D1
SH3GL1
SLC35E3
SORBS3
SPRED1
SPRED2
SRGAP2B
SSBP4
SWSAP1
SYNGR1
SYNGR3
SYP
TCF12
TCF4
TEKT4
TFG
TFIP11
TLE5
TMEM208
TMEM239
TOX2
TPD52
TRAF1
TRAF2
TRIB3
TRIM14
TRIM23
TRIM50
TRIM54
TRIM9
TSGA10IP
TSNAXIP1
TTC23L
TXN
TXNL4B
UFSP1
USHBP1
VMAC
VPS25
YPEL3
ZBTB42
ZMYND12
ZNF263
ZNF581
ZNF629
Entrez ID
57159
51324
HPRD ID
05928
10492
Ensembl ID
ENSG00000138100
ENSG00000090487
Uniprot IDs
Q9BYV2
A0A024R5Y1
Q9NZD8
PDB IDs
3Q1D
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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