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TRIM54 and UBE2D3
Data Source:
BioGRID
(pull down)
TRIM54
UBE2D3
Description
tripartite motif containing 54
ubiquitin conjugating enzyme E2 D3
Image
GO Annotations
Cellular Component
Cytoplasm
Microtubule
Microtubule Associated Complex
Z Disc
Nucleus
Nucleoplasm
Cytosol
Plasma Membrane
Endosome Membrane
Extracellular Exosome
Molecular Function
Protein Binding
Microtubule Binding
Zinc Ion Binding
Ubiquitin Protein Ligase Activity
Ubiquitin-protein Transferase Activity
Protein Binding
ATP Binding
Ubiquitin Protein Ligase Activity
Ubiquitin Conjugating Enzyme Activity
Biological Process
Microtubule-based Process
Negative Regulation Of Microtubule Depolymerization
Signal Transduction
Multicellular Organism Development
Protein Ubiquitination
Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase II
Protein Polyubiquitination
MyD88-independent Toll-like Receptor Signaling Pathway
DNA Repair
Cellular Protein Modification Process
Protein Monoubiquitination
Protein Targeting To Peroxisome
Apoptotic Process
Protein Ubiquitination
BMP Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Protein Autoubiquitination
Protein K48-linked Ubiquitination
Protein K11-linked Ubiquitination
Cellular Response To Cadmium Ion
Cellular Response To Mercury Ion
Positive Regulation Of Protein Targeting To Mitochondrion
Pathways
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
TICAM1, RIP1-mediated IKK complex recruitment
Signaling by BMP
Downregulation of SMAD2/3:SMAD4 transcriptional activity
E3 ubiquitin ligases ubiquitinate target proteins
Neddylation
Peroxisomal protein import
Negative regulators of DDX58/IFIH1 signaling
IKK complex recruitment mediated by RIP1
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Mean corpuscular hemoglobin (
32888494
)
Asthma and attention deficit hyperactivity disorder (
31619474
)
Diastolic blood pressure (
30224653
)
Interacting Genes
317 interacting genes:
AAMDC
ABHD17C
ADCY4
AGFG1
AIFM2
AK2
AK3
ANKRD11
ANKRD45
ARFIP2
ARHGAP29
ARHGEF5
ARHGEF6
ARMC7
ATXN3
ATXN3L
ATXN7
BBX
BMF
BSCL2
BYSL
C14orf39
C1orf109
C1orf216
C1orf35
C1QTNF2
C2CD6
C2orf49
C8orf74
CALM3
CARD9
CAVIN2
CBX8
CCDC102B
CCDC146
CCDC17
CCDC26
CCDC28A
CCDC87
CCHCR1
CCNC
CDC37
CDK18
CDKAL1
CDKN1A
CENPX
CEP57L1
CEP68
CFAP100
CFAP206
CFAP53
CHCHD2
CHD2
CHD3
CKM
CLPP
CMIP
CNGA3
CRADD
CSNK2B
CTNNA3
CWF19L2
CYTH4
DAXX
DCAF8
DCLRE1B
DCUN1D1
DDX6
DEUP1
DNAL4
DNASE1L1
DPYSL4
DRG2
DTNB
DTX2
DUSP16
DVL3
DYNC2I2
DYNLL1
EHHADH
EIF4E2
ELMO1
ELOA
ENKD1
EPHB2
EPM2AIP1
EXOC7
EXOC8
EXOSC5
EXTL2
FAM110A
FAM124A
FAM124B
FAM161A
FAM50B
FAM90A1
FAM9A
FARS2
FBF1
FBXO16
FBXW2
FLNC
FMNL1
G2E3
GAS8
GEM
GIMAP2
GLP2R
GMCL1
GNG13
GNL3L
GTF2I
GTF2IRD2
GTF2IRD2B
HAUS1
HBG1
HDAC10
HGS
HMMR
HOXB5
HSF2
HSPB1
HYAL2
IL18RAP
IL36A
IL4I1
ING3
INPP5J
IQUB
ITGAE
ITPKB
JOSD1
KANK2
KAT14
KDM1A
KIF9
KIFC3
KLHL38
KLHL42
KPNA2
KRT1
KRT3
KRT4
KRT6A
KRT6B
KRT6C
KRT75
KRT76
KRT78
KRT79
KRT8
KRTAP11-1
KRTAP9-2
LENG1
LIN37
LINC00887
LMO1
LMO2
LMO3
LMO4
LNX1
LSM2
MAD2L2
MAOB
MAPK3
MBD3
MCM7
MEAF6
MFAP1
MGARP
MICAL2
MID2
MNS1
MRTFA
MSH5
MYLK2
MYO15B
MYO5B
NEK6
NGLY1
NTAQ1
NUP54
NUP58
OFCC1
OSGIN1
OSTF1
OTUB1
OTUB2
PABPC3
PAIP2
PARVG
PCDHGB1
PCDHGC3
PCSK7
PDZK1IP1
PICK1
PIK3R3
PIWIL1
PLEKHM1
PLK4
PPIG
PPP1R18
PRF1
PRKAB2
PRKG1
PRMT5
PRPF18
PRR35
PSMA1
PYGM
RAB35
RABGEF1
RAD23A
RAPSN
RASSF10
RBM15B
RBM41
RCOR3
RELT
RIMS3
RNF4
RSRC2
RUNX1T1
SCNM1
SDCBP
SEC14L4
SELE
SEMA4C
SENP3
SH2D1B
SHC3
SLC13A2
SLITRK3
SMARCD1
SMARCE1
SNF8
SOX14
SPG21
SPRING1
SSX2IP
STAM
STRC
STXBP4
STYXL1
SYCE3
SYTL5
TBC1D22B
TCAF1
TCAP
TCEA2
TCEANC
TCHP
TEAD4
TEPSIN
THAP4
THOC1
TJAP1
TLE6
TLR10
TMEM30A
TNFAIP1
TNR
TRIM55
TRIM63
TRIM69
TRIML2
TSG101
TSHZ3
TSPEAR
TSSK3
TTC23
TTC9C
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E3
UBE2I
UBE2N
UBE2U
UBE2V2
UBL4A
UCHL1
UCHL3
UCHL5
USHBP1
USP15
USP18
USP2
USP21
USP33
USP35
USP4
USP5
USP7
USP8
UTP14C
VAMP4
VCAM1
VCP
VPS28
VPS9D1
XAF1
YEATS4
YOD1
ZBTB16
ZFHX3
ZGPAT
ZNF180
ZNF182
ZNF250
ZNF267
ZNF366
ZNF417
ZNF572
ZNF587
ZNF667-AS1
224 interacting genes:
AMBRA1
AMFR
ANAPC11
AREL1
ARIH1
ARIH2
BARD1
BFAR
BIRC2
BIRC3
BIRC7
BIRC8
BMI1
BRCA1
CADPS2
CBL
CBLC
CHFR
CNOT4
CSNK2A1
CUL4B
DBN1
DCUN1D1
DDX58
DTX1
DTX2
DTX3
DTX3L
DVL2
DZIP3
EPS15
ERGIC3
ESR1
F12
FBXL12
FBXL17
FBXL2
FBXO2
FBXO25
FBXO7
FBXW11
FBXW8
FOCAD
FZR1
H2AC4
H3C1
H4C1
HDAC6
HECTD1
HECW1
HECW2
HERC1
HERC2
HUWE1
IKBKG
ITCH
KAT2B
KDM1B
LRSAM1
MAEA
MAP3K1
MAPT
MARCHF3
MARCHF5
MARCHF7
MARCHF8
MAST1
MDM2
MDM4
MEX3B
MEX3C
MGRN1
MIB1
MID1
MID2
MKRN1
MKRN3
MSL1
MSL2
MUL1
MYCBP2
MYLIP
NBR1
NEDD4
NEDD4L
NFKB1
NFKBIA
NHLRC1
NOSIP
OTUB1
PCGF1
PCGF2
PCGF3
PCGF5
PCGF6
PCNA
PDCD5
PELI1
PER2
PJA1
PJA2
POLL
POLM
PRPF19
PTEN
RABGEF1
RBCK1
RBX1
RCHY1
RELA
RFFL
RFWD3
RING1
RLIM
RMND5B
RNF10
RNF103
RNF111
RNF114
RNF115
RNF122
RNF125
RNF126
RNF13
RNF130
RNF14
RNF150
RNF165
RNF166
RNF167
RNF168
RNF181
RNF185
RNF19B
RNF2
RNF216
RNF220
RNF25
RNF26
RNF31
RNF38
RNF4
RNF41
RNF43
RNF5
RNF8
RNFT1
RPLP1
RSPRY1
SAT1
SH3RF1
SHOC2
SIAH1
SIAH2
SMURF1
SMURF2
SOX2
SQSTM1
ST7
STAM2
STAU1
STK25
STUB1
SYVN1
TMEM129
TOPORS
TP53
TP73
TRAF6
TRAIP
TRIM10
TRIM17
TRIM2
TRIM23
TRIM25
TRIM26
TRIM27
TRIM28
TRIM31
TRIM32
TRIM33
TRIM35
TRIM37
TRIM38
TRIM39
TRIM43
TRIM45
TRIM5
TRIM50
TRIM54
TRIM55
TRIM58
TRIM62
TRIM63
TRIM68
TRIM69
TRIM7
TRIM72
TRIM8
TUBA1A
UBA1
UBA6
UBASH3B
UBE2O
UBE3A
UBE3C
UBE4A
UBE4B
UBOX5
UBR5
UBTD1
UFM1
UHRF1
USP7
UVSSA
WBP2
WSB1
WWP1
WWP2
XIAP
XPNPEP1
ZNRF1
ZNRF2
ZNRF4
Entrez ID
57159
7323
HPRD ID
05928
04269
Ensembl ID
ENSG00000138100
ENSG00000109332
Uniprot IDs
Q9BYV2
A0A024RDH2
D6RAH7
P61077
PDB IDs
3Q1D
1X23
2FUH
3L1Z
3RPG
3UGB
4BVU
4R8P
4S3O
5EGG
5IFR
6CP0
6T7F
Enriched GO Terms of Interacting Partners
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