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SPG21 and TFIP11
Data Source:
BioGRID
(two hybrid)
SPG21
TFIP11
Description
SPG21 abhydrolase domain containing, maspardin
tuftelin interacting protein 11
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Intracellular Membrane-bounded Organelle
Chromosome, Telomeric Region
Nucleoplasm
Spliceosomal Complex
Nucleolus
Cytoplasm
Nuclear Speck
Extracellular Matrix
U2-type Post-mRNA Release Spliceosomal Complex
Catalytic Step 2 Spliceosome
Molecular Function
Protein Binding
CD4 Receptor Binding
Nucleic Acid Binding
Protein Binding
Biological Process
Antigen Receptor-mediated Signaling Pathway
Spliceosomal Complex Disassembly
MRNA Splicing, Via Spliceosome
RNA Processing
Biomineral Tissue Development
Negative Regulation Of Protein-containing Complex Assembly
Protection From Non-homologous End Joining At Telomere
Negative Regulation Of Protein Binding
Negative Regulation Of DNA Ligase Activity
Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining
Pathways
mRNA Splicing - Major Pathway
Drugs
Diseases
Hereditary spastic paraplegia (SPG)
GWAS
Interacting Genes
164 interacting genes:
ACOT13
AGTR1
AGTRAP
AKIRIN2
APOC1
ARL6IP1
ARL8A
ARMC12
ARMC7
ATP5ME
ATPAF2
BORCS6
BSND
C10orf82
C9orf24
CCDC102B
CCDC153
CCDC33
CCHCR1
CD4
CDK2AP1
CDKN2B
CEP76
CEPT1
CFAP410
CIDEB
CLDN22
CMTM4
CMTM5
CMTM6
COG3
COG6
CPSF7
CRX
CRYAA
CRYAA2
CT55
CTIF
CTPS2
CUTC
DCTPP1
DTX2
DTX3L
EFHC2
EIF1B
EIF4H
EYA2
FAM114A1
FAM86C1P
FBXO44
FLACC1
GAD2
GAS8
GEMIN2
GEMIN4
GGA2
GOLGA2
GOLT1B
GRPEL1
GSK3A
HNRNPH1
HPRT1
HSD17B13
IKZF3
INCA1
IQCB1
KCTD9
KRT13
KRT15
KRT19
KRT31
LEPROTL1
LMNA
LMO1
LNX1
LSMEM2
MAB21L3
MID2
MPC2
MTMR9
MTUS2
MYG1
MYOG
N4BP3
NAB2
NDUFAF2
NIF3L1
NME4
NQO2
NR1D1
NRDE2
NUP54
PAX6
PBX4
PCBD2
PCNA
PDE5A
PEF1
PFDN5
PLP2
PNMA5
PPM1J
PRPS1
PRTFDC1
PSMB4
PTPA
RABAC1
RAD51C
REEP6
REL
ROPN1
RPRD1B
RPS19
RTL8B
RTN4
S100B
SATB1
SCAMP1
SEPTIN5
SFT2D1
SH3GL1
SLC35E3
SORBS3
SPRED1
SPRED2
SRGAP2B
SSBP4
SWSAP1
SYNGR1
SYNGR3
SYP
TCF12
TCF4
TEKT4
TFG
TFIP11
TLE5
TMEM208
TMEM239
TOX2
TPD52
TRAF1
TRAF2
TRIB3
TRIM14
TRIM23
TRIM50
TRIM54
TRIM9
TSGA10IP
TSNAXIP1
TTC23L
TXN
TXNL4B
UFSP1
USHBP1
VMAC
VPS25
YPEL3
ZBTB42
ZMYND12
ZNF263
ZNF581
ZNF629
232 interacting genes:
AARD
ABI2
ABLIM3
AIMP2
ANKRD11
AP1M1
ARHGEF9
ARMC7
ARMCX1
ARNT2
ATP5PO
ATPAF2
AXIN1
BAZ2B
BCL6
BHLHA9
BMF
BRD1
BYSL
C1orf109
C2CD6
CARD9
CAVIN3
CBX8
CCDC102B
CCDC116
CCDC120
CCDC121
CCDC13
CCDC146
CCDC187
CCDC196
CCDC42
CCDC57
CCDC6
CCDC68
CCDC96
CCHCR1
CCND3
CCNG1
CCNL1
CCP110
CDKN1A
CDR2L
CENPU
CEP57
CEP57L1
CEP95
CFAP206
COQ8A
COX5B
CT55
CWF19L2
DAXX
DDX25
DES
DGCR6
DISC1
DPPA3
DTNB
EAF2
EIF3A
EIF3D
ENOX2
EPM2AIP1
EXOC3L1
EXOC8
EXOSC5
FAM13C
FAM156A
FAM161A
FAM161B
FAM50B
FAM81A
FAM90A1
FANCG
FGA
GADD45GIP1
GAS2L2
GCC1
GCFC2
GEM
GFAP
GNG4
GOLGA1
GOLGA2
GPS2
GRAP2
GSE1
HAUS1
HDAC4
HIP1R
HMG20B
HOOK1
HSF2BP
IKBIP
IL16
IMP3
JRK
KANK2
KANSL1
KAT5
KDM1A
KIF3C
KIF9
KIFC3
KIZ
KRT1
KRT20
KRT6A
KRT6B
KRT6C
KRT8
LATS1
LCA5
LCA5L
LENG1
LIN37
LMNB2
LMO1
LMO2
LMO4
LSM3
LSP1P3
LYSMD1
MAB21L2
MCM7
MDM2
METTL17
MFAP1
MKRN3
MRPL11
MTFR2
MXD3
MYO15B
MYOM1
NDC80
NDE1
NDN
NEK6
NFKBID
NFU1
NSMF
NUP88
ODAD3
OIP5
PBX3
PBX4
PCM1
PDE4DIP
PHF1
PIBF1
PICK1
PKN3
PLK4
POLL
POLR1C
POM121
PPFIA3
PPP1R16A
PPP1R16B
PPP1R18
PRPF31
PSMA4
PSMC5
PSTPIP1
PTCD1
RCOR3
RHNO1
RIN1
RNF6
RRP7A
RUNX1T1
RXRB
S100P
SAP30BP
SCNM1
SFR1
SGF29
SH2D4A
SH3GLB1
SMARCB1
SMARCE1
SNAPIN
SNRPB
SNW1
SNX20
SNX32
SOGA1
SPG21
SSX2IP
STRA8
STRN
SYCE1
TBC1D30
TBRG4
TCAF1
TDP2
TFPT
THAP7
THAP8
TNNT1
TP53
TRAF3IP3
TRAPPC4
TRIM45
TRIML2
TSG101
TSGA10IP
TSHZ2
TSHZ3
TSPYL4
TUFT1
TXLNA
TXN2
UBTFL1
USP2
USP6
USP7
VPS37C
VPS39
WAC
WASHC3
ZC2HC1C
ZFYVE26
ZGPAT
ZMAT2
ZNF417
ZNF572
ZNF587
ZNF777
ZSCAN12
Entrez ID
51324
24144
HPRD ID
10492
11628
Ensembl ID
ENSG00000090487
ENSG00000100109
Uniprot IDs
A0A024R5Y1
Q9NZD8
A0A024R1I7
Q9UBB9
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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