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SPG21 and NAB2
Data Source:
BioGRID
(two hybrid)
SPG21
NAB2
Description
SPG21 abhydrolase domain containing, maspardin
NGFI-A binding protein 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Intracellular Membrane-bounded Organelle
Nucleus
Molecular Function
Protein Binding
CD4 Receptor Binding
Transcription Coregulator Activity
Transcription Corepressor Activity
Protein Binding
Transcription Factor Binding
Identical Protein Binding
Biological Process
Antigen Receptor-mediated Signaling Pathway
Endochondral Ossification
Regulation Of Transcription, DNA-templated
Schwann Cell Differentiation
Negative Regulation Of Transcription By RNA Polymerase III
Myelination
Regulation Of Epidermis Development
Positive Regulation Of Tau-protein Kinase Activity
Pathways
NGF-stimulated transcription
NGF-stimulated transcription
EGR2 and SOX10-mediated initiation of Schwann cell myelination
Drugs
Diseases
Hereditary spastic paraplegia (SPG)
GWAS
Allergic disease (asthma, hay fever or eczema) (
29785011
)
Asthma (
31361310
31959851
31619474
29273806
)
Asthma (adult onset) (
31036433
)
Asthma (childhood onset) (
31036433
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Bipolar disorder (
31043756
)
IgE levels (
22075330
)
Schizophrenia (
25056061
29483656
)
Interacting Genes
164 interacting genes:
ACOT13
AGTR1
AGTRAP
AKIRIN2
APOC1
ARL6IP1
ARL8A
ARMC12
ARMC7
ATP5ME
ATPAF2
BORCS6
BSND
C10orf82
C9orf24
CCDC102B
CCDC153
CCDC33
CCHCR1
CD4
CDK2AP1
CDKN2B
CEP76
CEPT1
CFAP410
CIDEB
CLDN22
CMTM4
CMTM5
CMTM6
COG3
COG6
CPSF7
CRX
CRYAA
CRYAA2
CT55
CTIF
CTPS2
CUTC
DCTPP1
DTX2
DTX3L
EFHC2
EIF1B
EIF4H
EYA2
FAM114A1
FAM86C1P
FBXO44
FLACC1
GAD2
GAS8
GEMIN2
GEMIN4
GGA2
GOLGA2
GOLT1B
GRPEL1
GSK3A
HNRNPH1
HPRT1
HSD17B13
IKZF3
INCA1
IQCB1
KCTD9
KRT13
KRT15
KRT19
KRT31
LEPROTL1
LMNA
LMO1
LNX1
LSMEM2
MAB21L3
MID2
MPC2
MTMR9
MTUS2
MYG1
MYOG
N4BP3
NAB2
NDUFAF2
NIF3L1
NME4
NQO2
NR1D1
NRDE2
NUP54
PAX6
PBX4
PCBD2
PCNA
PDE5A
PEF1
PFDN5
PLP2
PNMA5
PPM1J
PRPS1
PRTFDC1
PSMB4
PTPA
RABAC1
RAD51C
REEP6
REL
ROPN1
RPRD1B
RPS19
RTL8B
RTN4
S100B
SATB1
SCAMP1
SEPTIN5
SFT2D1
SH3GL1
SLC35E3
SORBS3
SPRED1
SPRED2
SRGAP2B
SSBP4
SWSAP1
SYNGR1
SYNGR3
SYP
TCF12
TCF4
TEKT4
TFG
TFIP11
TLE5
TMEM208
TMEM239
TOX2
TPD52
TRAF1
TRAF2
TRIB3
TRIM14
TRIM23
TRIM50
TRIM54
TRIM9
TSGA10IP
TSNAXIP1
TTC23L
TXN
TXNL4B
UFSP1
USHBP1
VMAC
VPS25
YPEL3
ZBTB42
ZMYND12
ZNF263
ZNF581
ZNF629
80 interacting genes:
ANK3
ANKRD11
CBX8
CCDC187
CCDC33
CCDC57
CCHCR1
CDC23
CTAG1A
CTAG1B
CTNNA3
CWF19L2
DDX6
DGCR6
DGCR6L
DRG2
EGR1
EGR2
ELOA
ENKD1
EXOC8
FAM9A
GCC1
GOLGA6L9
HSF2BP
JAKMIP2
KIF9
KIFC3
KRT34
KRT40
KRTAP10-3
KRTAP10-8
LENG1
LMNA
LNX1
MAPK3
MCM7
MCRS1
MDFI
MORF4L1
MORF4L2
NDOR1
NEDD9
NME7
NOTCH2NLA
NTAQ1
PHF1
PHOSPHO2
PIK3R3
PIN1
PLOD3
PRKAA2
PRKAB2
PSMA1
QARS1
RBPMS
RFC5
RINT1
SCNM1
SMARCD1
SORBS3
SPG21
SUMO1P1
TCEA2
TCEANC
TCHP
TGIF2LY
TLE5
TRAF2
TRIM23
TSGA10
TSGA10IP
TTC19
USP2
UTP14C
ZBED8
ZMAT2
ZMYND12
ZMYND19
ZNF417
Entrez ID
51324
4665
HPRD ID
10492
03854
Ensembl ID
ENSG00000090487
ENSG00000166886
Uniprot IDs
A0A024R5Y1
Q9NZD8
Q15742
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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