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SPG21 and TRIM50
Data Source:
BioGRID
(two hybrid)
SPG21
TRIM50
Description
SPG21 abhydrolase domain containing, maspardin
tripartite motif containing 50
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Golgi Apparatus
Cytosol
Endosome Membrane
Trans-Golgi Network Transport Vesicle
Intracellular Membrane-bounded Organelle
Cytoplasm
Cytosol
Molecular Function
Protein Binding
CD4 Receptor Binding
Protein Binding
Zinc Ion Binding
Identical Protein Binding
Ubiquitin Protein Ligase Activity
Biological Process
Antigen Receptor-mediated Signaling Pathway
Protein Ubiquitination
Pathways
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
Hereditary spastic paraplegia (SPG)
GWAS
Immune reponse to smallpox (secreted IL-12p40) (
22610502
)
Interacting Genes
164 interacting genes:
ACOT13
AGTR1
AGTRAP
AKIRIN2
APOC1
ARL6IP1
ARL8A
ARMC12
ARMC7
ATP5ME
ATPAF2
BORCS6
BSND
C10orf82
C9orf24
CCDC102B
CCDC153
CCDC33
CCHCR1
CD4
CDK2AP1
CDKN2B
CEP76
CEPT1
CFAP410
CIDEB
CLDN22
CMTM4
CMTM5
CMTM6
COG3
COG6
CPSF7
CRX
CRYAA
CRYAA2
CT55
CTIF
CTPS2
CUTC
DCTPP1
DTX2
DTX3L
EFHC2
EIF1B
EIF4H
EYA2
FAM114A1
FAM86C1P
FBXO44
FLACC1
GAD2
GAS8
GEMIN2
GEMIN4
GGA2
GOLGA2
GOLT1B
GRPEL1
GSK3A
HNRNPH1
HPRT1
HSD17B13
IKZF3
INCA1
IQCB1
KCTD9
KRT13
KRT15
KRT19
KRT31
LEPROTL1
LMNA
LMO1
LNX1
LSMEM2
MAB21L3
MID2
MPC2
MTMR9
MTUS2
MYG1
MYOG
N4BP3
NAB2
NDUFAF2
NIF3L1
NME4
NQO2
NR1D1
NRDE2
NUP54
PAX6
PBX4
PCBD2
PCNA
PDE5A
PEF1
PFDN5
PLP2
PNMA5
PPM1J
PRPS1
PRTFDC1
PSMB4
PTPA
RABAC1
RAD51C
REEP6
REL
ROPN1
RPRD1B
RPS19
RTL8B
RTN4
S100B
SATB1
SCAMP1
SEPTIN5
SFT2D1
SH3GL1
SLC35E3
SORBS3
SPRED1
SPRED2
SRGAP2B
SSBP4
SWSAP1
SYNGR1
SYNGR3
SYP
TCF12
TCF4
TEKT4
TFG
TFIP11
TLE5
TMEM208
TMEM239
TOX2
TPD52
TRAF1
TRAF2
TRIB3
TRIM14
TRIM23
TRIM50
TRIM54
TRIM9
TSGA10IP
TSNAXIP1
TTC23L
TXN
TXNL4B
UFSP1
USHBP1
VMAC
VPS25
YPEL3
ZBTB42
ZMYND12
ZNF263
ZNF581
ZNF629
40 interacting genes:
ARHGAP45
CDK18
CLK2
EFHC2
EPM2AIP1
FAM221B
GCC1
HDAC6
IQUB
KLHL2
L3MBTL2
LNX1
MEOX2
PIAS2
PLA2G6
RAD23A
RSPH14
SNAI1
SPG21
SRC
TEPSIN
TRAF2
TRIM27
TSGA10IP
TSSK3
UBASH3A
UBE2D1
UBE2D2
UBE2D3
UBE2D4
UBE2E1
UBE2E2
UBE2E3
UBE2K
UBE2N
UBTD1
USP2
XAF1
ZNF438
ZNF620
Entrez ID
51324
135892
HPRD ID
10492
15566
Ensembl ID
ENSG00000090487
ENSG00000146755
Uniprot IDs
A0A024R5Y1
Q9NZD8
B7ZLG2
Q2M204
Q86XT4
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Difference)
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Tagcloud (Intersection)
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