DDX4 and RANBP9

Data Source:
HPRD (two hybrid, in vivo)

		DDX4	RANBP9
Description		DEAD-box helicase 4	RAN binding protein 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm P Granule Perinuclear Region Of Cytoplasm Pi-body PiP-body	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body
	Molecular Function	RNA Binding RNA Helicase Activity ATP Binding ATPase Activity	Protein Binding Enzyme Binding
	Biological Process	Male Meiotic Nuclear Division Male Meiosis I Multicellular Organism Development Gamete Generation Spermatogenesis Negative Regulation Of Transposition Cell Differentiation Flagellated Sperm Motility Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation PiRNA Biosynthetic Process	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process
Pathways		PIWI-interacting RNA (piRNA) biogenesis	L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling
Drugs
Diseases
GWAS		Cocaine dependence ( 31212010)	Breast cancer ( 29059683 23535729)
Interacting Genes		5 interacting genes: PIWIL2 RANBP9 SPSB1 SPSB2 SPSB4	56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5
Entrez ID		54514	10048
HPRD ID		05593	04835
Ensembl ID		ENSG00000152670	ENSG00000010017
Uniprot IDs		Q9NQI0	A0A024QZW3 Q96S59
PDB IDs			5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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