RANBP9 and HNF4G

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RANBP9	HNF4G
Description		RAN binding protein 9	hepatocyte nuclear factor 4 gamma
Image
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body	Chromatin Nucleoplasm Cytosol Intercellular Bridge Mitotic Spindle
	Molecular Function	Protein Binding Enzyme Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Nuclear Receptor Activity Zinc Ion Binding
	Biological Process	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Cell Differentiation Intracellular Receptor Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Development
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling	Regulation of gene expression in beta cells Nuclear Receptor transcription pathway
Drugs			Palmitic Acid
Diseases
GWAS		Breast cancer ( 29059683 23535729)	Adult body size ( 32376654) Attention function ( 29907492) BMI (adjusted for smoking behaviour) ( 28443625) BMI in non-smokers ( 28443625) Body mass index ( 26426971 28892062 25673413 20935630 28448500) Body mass index (age <50) ( 26426971) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (joint analysis main effects and smoking interaction) ( 28443625) Body mass index in physically active individuals ( 28448500) Body mass index in physically inactive individuals ( 28448500) Body mass index x sex x age interaction (4df test) ( 26426971) Body size at age 10 ( 32376654) Breast cancer ( 29059683 23535729) Chronotype ( 30696823) Estimated glomerular filtration rate ( 31152163) Morning person ( 30696823) Number of sexual partners ( 30643258) Obesity ( 23563607) Pancreatic cancer ( 29422604) Pulse pressure ( 27841878) Red blood cell count ( 32888494) Serum uric acid levels ( 30993211 29403010) Systolic blood pressure ( 27841878) Urate levels ( 31985003 31578528 23263486) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5	15 interacting genes: COPS5 DNMT3L GAPDH HAX1 HLF NCOA1 NR0B2 NSD1 PNRC1 PNRC2 PRDX6 PSMC5 RANBP9 TNNI2 ZNF629
Entrez ID		10048	3174
HPRD ID		04835	06909
Ensembl ID		ENSG00000010017	ENSG00000164749
Uniprot IDs		A0A024QZW3 Q96S59	F1D8Q4 Q14541
PDB IDs		5JI7 5JI9 5JIU	1LV2
Enriched GO Terms of Interacting Partners?
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