RANBP9 and ENTPD1

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vivo)

		RANBP9	ENTPD1
Description		RAN binding protein 9	ectonucleoside triphosphate diphosphohydrolase 1
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body	Plasma Membrane Integral Component Of Plasma Membrane Membrane Extracellular Exosome
	Molecular Function	Protein Binding Enzyme Binding	Guanosine-diphosphatase Activity Protein Binding ATP Binding Nucleoside-diphosphatase Activity Uridine-diphosphatase Activity DATP Phosphohydrolase Activity DCTP Phosphohydrolase Activity DUTP Phosphohydrolase Activity DTTP Phosphohydrolase Activity GTP Phosphohydrolase Activity 8-oxo-dGTP Phosphohydrolase Activity DGTP Phosphohydrolase Activity
	Biological Process	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Cell Adhesion Blood Coagulation Nucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling	Phosphate bond hydrolysis by NTPDase proteins Purinergic signaling in leishmaniasis infection
Drugs
Diseases			Premature ovarian failure
GWAS		Breast cancer ( 29059683 23535729)	Blood protein levels ( 30072576 29875488) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5	1 interacting genes: RANBP9
Entrez ID		10048	953
HPRD ID		04835	09047
Ensembl ID		ENSG00000010017	ENSG00000138185
Uniprot IDs		A0A024QZW3 Q96S59	P49961
PDB IDs		5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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