RANBP9 and RAN

Data Source:
HPRD (in vivo, in vitro)

		RANBP9	RAN
Description		RAN binding protein 9	RAN, member RAS oncogene family
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GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body	Chromatin Nucleus Nuclear Envelope Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Centriole Cytosol Membrane Midbody Protein-containing Complex Melanosome RNA Nuclear Export Complex Host Cell Recycling Endosome Extracellular Exosome Flemming Body
	Molecular Function	Protein Binding Enzyme Binding	Magnesium Ion Binding Chromatin Binding RNA Binding GTPase Activity Nuclear Export Signal Receptor Activity Protein Binding GTP Binding GDP Binding Cadherin Binding Protein Heterodimerization Activity Pre-miRNA Binding
	Biological Process	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Ribosomal Subunit Export From Nucleus Ribosomal Large Subunit Export From Nucleus Ribosomal Small Subunit Export From Nucleus Mitotic Sister Chromatid Segregation Mitotic Cell Cycle DNA Metabolic Process TRNA Export From Nucleus Protein Import Into Nucleus Protein Export From Nucleus Mitotic Spindle Organization MiRNA Metabolic Process Viral Process Positive Regulation Of Protein Binding Pre-miRNA Export From Nucleus Positive Regulation Of Protein Import Into Nucleus Regulation Of Cholesterol Biosynthetic Process GTP Metabolic Process Cell Division SnRNA Import Into Nucleus Intracellular Transport Of Virus Protein Localization To Nucleolus
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling	Rev-mediated nuclear export of HIV RNA Regulation of cholesterol biosynthesis by SREBP (SREBF) NEP/NS2 Interacts with the Cellular Export Machinery Nuclear import of Rev protein MicroRNA (miRNA) biogenesis Transcriptional regulation by small RNAs tRNA processing in the nucleus Postmitotic nuclear pore complex (NPC) reformation Postmitotic nuclear pore complex (NPC) reformation
Drugs			Guanosine-5'-Diphosphate
Diseases
GWAS		Breast cancer ( 29059683 23535729)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5	58 interacting genes: ABL1 ADRB2 AR ASAP2 BCAR1 BIRC5 BMPR1B CEP126 CSE1L DUX4 EP300 GADD45G GIT1 IPO11 IPO13 IPO5 IPO7 KPNA2 KPNB1 MBP MSL1 NEK9 NR3C1 NSMF NUP153 NUP50 NUTF2 NXF1 NXT1 PAK4 PARP10 PTMA RANBP1 RANBP10 RANBP2 RANBP3 RANBP9 RANGAP1 RANGRF RCC1 RGPD5 RPL7 SMAD1 SMAD2 SMARCB1 SMURF2 SNUPN SPAG8 SSRP1 SUMO2 TGFBR1 TNPO1 TNPO2 XPO1 XPO4 XPO5 XPO7 XPOT
Entrez ID		10048	5901
HPRD ID		04835	03109
Ensembl ID		ENSG00000010017	ENSG00000132341
Uniprot IDs		A0A024QZW3 Q96S59	B4DV51 P62826
PDB IDs		5JI7 5JI9 5JIU	1I2M 1IBR 1K5D 1K5G 1QBK 1RRP 2MMC 2MMG 2N1B 3CH5 3EA5 3GJ0 3GJ3 3GJ4 3GJ5 3GJ6 3GJ7 3GJ8 3GJX 3NBY 3NBZ 3NC0 3NC1 3ZJY 4C0Q 4GMX 4GPT 4HAT 4HAU 4HAV 4HAW 4HAX 4HAY 4HAZ 4HB0 4HB2 4HB3 4HB4 4OL0 4WVF 5CIQ 5CIT 5CIW 5CJ2 5CLL 5CLQ 5DH9 5DHA 5DHF 5DI9 5DIF 5DIS 5DLQ 5FYQ 5JLJ 5UWH 5UWI 5UWJ 5UWO 5UWP 5UWQ 5UWR 5UWS 5UWT 5UWU 5UWW 5YRO 5YST 5YSU 5YTB 5ZPU 6A38 6A3A 6A3B 6A3C 6A3E 6CIT 6KFT 6Q82 6Q84 6TVO 6X2M 6X2O 6X2P 6X2R 6X2S 6X2U 6X2V 6X2W 6X2X 6X2Y
Enriched GO Terms of Interacting Partners?
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