RANBP9 and YPEL5

Data Source:
BioGRID (affinity chromatography technology, two hybrid, affinity chromatography technology)

		RANBP9	YPEL5
Description		RAN binding protein 9	yippee like 5
Image			No pdb structure
GO Annotations	Cellular Component	Ubiquitin Ligase Complex Nucleus Nucleoplasm Cytoplasm Cytosol Microtubule Associated Complex Plasma Membrane Nuclear Body	Ubiquitin Ligase Complex Extracellular Region Nucleus Centrosome Midbody Mitotic Spindle Pole Tertiary Granule Lumen Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Enzyme Binding	Protein Binding Metal Ion Binding
	Biological Process	MAPK Cascade Cytoskeleton Organization Microtubule Nucleation Cell Surface Receptor Signaling Pathway Axon Guidance Protein-containing Complex Assembly Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Amyloid Precursor Protein Catabolic Process	Cell Population Proliferation Neutrophil Degranulation
Pathways		L1CAM interactions RAF/MAP kinase cascade MET activates RAS signaling	Neutrophil degranulation
Drugs
Diseases
GWAS		Breast cancer ( 29059683 23535729)	Celiac disease and Rheumatoid arthritis ( 26546613) Triglyceride levels x short total sleep time interaction (2df test) ( 31719535)
Interacting Genes		56 interacting genes: ADAP1 ADAP2 APC AR ATM AXL BACE1 BRCA1 CACNA1G CALB1 CBS CCND1 CDK11B CLEC7A DDX4 DISC1 DYRK1B ENTPD1 ESR1 EXOC2 FMR1 HIPK2 HMBS HNF4G ITGAL ITGB2 L1CAM LMNA MAPK6 MET MPHOSPH8 NCOA6 NCOR2 NSRP1 PPARD PPARG PPP1CA PRKACA RAF1 RAN S100A7 SMAD2 SMAD3 SMAD9 SOS1 SPOP SPP1 TFRC THRA THRB TP53 TP73 UCHL1 USP11 WNK1 YPEL5	13 interacting genes: CTDSP1 DDIT4L FBXO7 GSC2 MAEA MAPKBP1 PFDN5 PLAGL2 PSMA1 RANBP9 SHC3 TRAF5 ZNF655
Entrez ID		10048	51646
HPRD ID		04835	18312
Ensembl ID		ENSG00000010017	ENSG00000119801
Uniprot IDs		A0A024QZW3 Q96S59	P62699
PDB IDs		5JI7 5JI9 5JIU
Enriched GO Terms of Interacting Partners?
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