MT-CO1 and PRDX4

Data Source:
BioGRID (two hybrid)

		MT-CO1	PRDX4
Description		cytochrome c oxidase subunit I	peroxiredoxin 4
Image
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV Integral Component Of Membrane Respiratory Chain Complex IV	Extracellular Region Nucleus Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Heme Binding Metal Ion Binding	Protein Binding Thioredoxin Peroxidase Activity
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Response To Oxidative Stress Aging Aerobic Respiration Electron Transport Coupled Proton Transport Cerebellum Development Respiratory Electron Transport Chain Response To Copper Ion Response To Electrical Stimulus	Response To Oxidative Stress I-kappaB Phosphorylation Spermatogenesis Male Gonad Development Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Cellular Response To Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Male Germ Cell Proliferation
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport	Neutrophil degranulation
Drugs		Cholic Acid N-Formylmethionine Oxygen
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS
Interacting Genes		10 interacting genes: CDC42 CLEC4G COX4I1 COX5A HSPB2 KCNMB1 LIG4 MEOX2 PRDX4 SNCA	25 interacting genes: A1BG ALG12 APOB CFHR1 CFHR3 CLIC1 CYP27A1 DUSP23 GLTPD2 HDAC6 LBP MAP4K2 MT-CO1 NR4A1 PLG PRDX1 PRDX2 PRDX3 RCHY1 SULT2A1 SUMO4 TBXA2R TTF2 UBC VTN
Entrez ID		4512	10549
HPRD ID		02469	05935
Ensembl ID		ENSG00000198804	ENSG00000123131
Uniprot IDs		A0A1X7RBG2 P00395 U5YWV7	Q13162 V9HW63
PDB IDs		5Z62	2PN8 3TJB 3TJF 3TJG 3TJJ 3TJK 3TKP 3TKQ 3TKR 3TKS 4RQX 5HQP
Enriched GO Terms of Interacting Partners?
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