MT-CO1 and KCNMB1

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		MT-CO1	KCNMB1
Description		cytochrome c oxidase subunit I	potassium calcium-activated channel subfamily M regulatory beta subunit 1
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV Integral Component Of Membrane Respiratory Chain Complex IV	Plasma Membrane Voltage-gated Potassium Channel Complex Synapse
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Heme Binding Metal Ion Binding	Calcium-activated Potassium Channel Activity Potassium Channel Regulator Activity
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Response To Oxidative Stress Aging Aerobic Respiration Electron Transport Coupled Proton Transport Cerebellum Development Respiratory Electron Transport Chain Response To Copper Ion Response To Electrical Stimulus	Detection Of Calcium Ion Potassium Ion Transport Chemical Synaptic Transmission Aging Cellular Response To Ethanol Cellular Response To Hypoxia Potassium Ion Transmembrane Transport Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Response To Bile Acid
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport	Ca2+ activated K+ channels cGMP effects
Drugs		Cholic Acid N-Formylmethionine Oxygen	Procaine Miconazole Trimebutine
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS			Acne (severe) ( 24927181) Liver transplant-free survival in primary sclerosing cholangitis (time to event) ( 28779025)
Interacting Genes		10 interacting genes: CDC42 CLEC4G COX4I1 COX5A HSPB2 KCNMB1 LIG4 MEOX2 PRDX4 SNCA	5 interacting genes: CLCA1 EWSR1 KCNMA1 MT-CO1 STX8
Entrez ID		4512	3779
HPRD ID		02469	10358
Ensembl ID		ENSG00000198804	ENSG00000145936
Uniprot IDs		A0A1X7RBG2 P00395 U5YWV7	Q16558
PDB IDs		5Z62
Enriched GO Terms of Interacting Partners?
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