MT-CO1 and COX4I1

Data Source:
HPRD (in vivo)

		MT-CO1	COX4I1
Description		cytochrome c oxidase subunit I	cytochrome c oxidase subunit 4I1
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV Integral Component Of Membrane Respiratory Chain Complex IV	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV Cytosol Membrane Integral Component Of Membrane
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Heme Binding Metal Ion Binding	Cytochrome-c Oxidase Activity Protein Binding
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Response To Oxidative Stress Aging Aerobic Respiration Electron Transport Coupled Proton Transport Cerebellum Development Respiratory Electron Transport Chain Response To Copper Ion Response To Electrical Stimulus	Generation Of Precursor Metabolites And Energy Mitochondrial Electron Transport, Cytochrome C To Oxygen Response To Nutrient Proton Transmembrane Transport
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport	TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs		Cholic Acid N-Formylmethionine Oxygen	Cholic Acid N-Formylmethionine
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS			Leprosy ( 25642632) Thiazide-induced adverse metabolic effects in hypertensive patients ( 23400010)
Interacting Genes		10 interacting genes: CDC42 CLEC4G COX4I1 COX5A HSPB2 KCNMB1 LIG4 MEOX2 PRDX4 SNCA	5 interacting genes: APP MT-CO1 SDCBP TRIM55 TRIM63
Entrez ID		4512	1327
HPRD ID		02469	00466
Ensembl ID		ENSG00000198804	ENSG00000131143
Uniprot IDs		A0A1X7RBG2 P00395 U5YWV7	H3BNV9 P13073 Q86WV2
PDB IDs		5Z62	5Z62
Enriched GO Terms of Interacting Partners?
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