PRDX4 and SUMO4

Data Source:
HPRD (in vivo)

		PRDX4	SUMO4
Description		peroxiredoxin 4	small ubiquitin like modifier 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleus SUMO Ligase Complex
	Molecular Function	Protein Binding Thioredoxin Peroxidase Activity	Molecular_function Protein Tag Ubiquitin-like Protein Ligase Binding
	Biological Process	Response To Oxidative Stress I-kappaB Phosphorylation Spermatogenesis Male Gonad Development Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Cellular Response To Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Male Germ Cell Proliferation	Protein Sumoylation Cellular Response To Oxidative Stress Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of DNA Binding Negative Regulation Of DNA Binding Negative Regulation Of Transcription, DNA-templated Regulation Of Protein Localization To Nucleus
Pathways		Neutrophil degranulation
Drugs
Diseases
GWAS			Dupuytren's disease ( 28886342)
Interacting Genes		25 interacting genes: A1BG ALG12 APOB CFHR1 CFHR3 CLIC1 CYP27A1 DUSP23 GLTPD2 HDAC6 LBP MAP4K2 MT-CO1 NR4A1 PLG PRDX1 PRDX2 PRDX3 RCHY1 SULT2A1 SUMO4 TBXA2R TTF2 UBC VTN	75 interacting genes: ACADM ACO2 ACTG1 ALDOA ARHGDIA ATP5F1B CALR CAT CCT2 CCT5 CCT6A CCT7 CLIC1 DNAJA1 DNAJB11 EIF3I ENO1 ENO2 FOS G6PD GAPDH GMPS GSTP1 HNRNPD HNRNPF HNRNPH1 HNRNPL HSPA1B HSPA5 HSPA8 HSPA9 HSPD1 IDH1 IDH3A IMPDH2 JUN LDHB LMNA LMNB1 MRPS22 NFKBIA NR3C1 PA2G4 PAFAH1B3 PDIA3 PDIA6 PGK1 PHB PHGDH PITHD1 PPA1 PRDX2 PRDX3 PRDX4 PRDX6 PRPS1 PSMC2 RACK1 RPSA SF3B4 SPINT2 STAT1 STAT3 STIP1 STOML2 STRAP TFAP2A TOP2A TPM3 TUBA1C TXNL1 UBE2V1 VCP VDAC1 ZPR1
Entrez ID		10549	387082
HPRD ID		05935	10584
Ensembl ID		ENSG00000123131	ENSG00000177688
Uniprot IDs		Q13162 V9HW63	Q6EEV6
PDB IDs		2PN8 3TJB 3TJF 3TJG 3TJJ 3TJK 3TKP 3TKQ 3TKR 3TKS 4RQX 5HQP
Enriched GO Terms of Interacting Partners?
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