MT-CO1 and COX5A

Data Source:
HPRD (in vivo)

		MT-CO1	COX5A
Description		cytochrome c oxidase subunit I	cytochrome c oxidase subunit 5A
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex III Mitochondrial Respiratory Chain Complex IV Integral Component Of Membrane Respiratory Chain Complex IV	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex IV
	Molecular Function	Cytochrome-c Oxidase Activity Protein Binding Heme Binding Metal Ion Binding	Cytochrome-c Oxidase Activity Protein Binding Electron Transfer Activity Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, Cytochrome C To Oxygen Response To Oxidative Stress Aging Aerobic Respiration Electron Transport Coupled Proton Transport Cerebellum Development Respiratory Electron Transport Chain Response To Copper Ion Response To Electrical Stimulus	Mitochondrial Electron Transport, Cytochrome C To Oxygen Proton Transmembrane Transport
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport	TP53 Regulates Metabolic Genes Respiratory electron transport
Drugs		Cholic Acid N-Formylmethionine Oxygen	Cholic Acid N-Formylmethionine
Diseases		Leber optic atrophy; Leber hereditary optic atrophy (LHON)
GWAS			Caffeine consumption ( 21490707) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Neutrophil percentage of white cells ( 32888494) Systolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858)
Interacting Genes		10 interacting genes: CDC42 CLEC4G COX4I1 COX5A HSPB2 KCNMB1 LIG4 MEOX2 PRDX4 SNCA	9 interacting genes: COPS6 EPM2A EXOSC8 HTRA1 KRT31 KRT40 MESD MT-CO1 SPDEF
Entrez ID		4512	9377
HPRD ID		02469	04799
Ensembl ID		ENSG00000198804	ENSG00000178741
Uniprot IDs		A0A1X7RBG2 P00395 U5YWV7	P20674
PDB IDs		5Z62	5Z62
Enriched GO Terms of Interacting Partners?
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