PRDX4 and DUSP23

Data Source:
BioGRID (two hybrid)

		PRDX4	DUSP23
Description		peroxiredoxin 4	dual specificity phosphatase 23
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GO Annotations	Cellular Component	Extracellular Region Nucleus Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen	Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding Thioredoxin Peroxidase Activity	Protein Tyrosine Phosphatase Activity Protein Binding Protein Tyrosine/serine/threonine Phosphatase Activity Phosphatase Activity Protein Serine Phosphatase Activity Protein Threonine Phosphatase Activity
	Biological Process	Response To Oxidative Stress I-kappaB Phosphorylation Spermatogenesis Male Gonad Development Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Cellular Response To Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Male Germ Cell Proliferation	Dephosphorylation Peptidyl-tyrosine Dephosphorylation
Pathways		Neutrophil degranulation
Drugs			4-Nitrophenyl Phosphate
Diseases
GWAS			Bone mineral density (Ward's triangle area) ( 27397699) C-reactive protein ( 22939635) Interstitial lung disease ( 21787189)
Interacting Genes		25 interacting genes: A1BG ALG12 APOB CFHR1 CFHR3 CLIC1 CYP27A1 DUSP23 GLTPD2 HDAC6 LBP MAP4K2 MT-CO1 NR4A1 PLG PRDX1 PRDX2 PRDX3 RCHY1 SULT2A1 SUMO4 TBXA2R TTF2 UBC VTN	32 interacting genes: ASB13 ASB6 BANF2 CCDC186 CEP126 DBI DBN1 DDIT4L DNMT3B EDRF1 EED EXOSC8 GCM1 KAT5 KBTBD7 MKRN1 MRNIP MRPL20 MTFR1 NIF3L1 PRDX4 PSMB8 PSME2 RPL8 RUFY2 SHC1 SMPD1 TCF4 TMOD3 TUBA1A UBA3 ZNF746
Entrez ID		10549	54935
HPRD ID		05935	07908
Ensembl ID		ENSG00000123131	ENSG00000158716
Uniprot IDs		Q13162 V9HW63	A0A140VJI5 Q9BVJ7
PDB IDs		2PN8 3TJB 3TJF 3TJG 3TJJ 3TJK 3TKP 3TKQ 3TKR 3TKS 4RQX 5HQP	2IMG 4ERC
Enriched GO Terms of Interacting Partners?
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