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KPNA2 and NFKBIB
Data Source:
HPRD
(in vitro)
KPNA2
NFKBIB
Description
karyopherin subunit alpha 2
NFKB inhibitor beta
Image
No pdb structure
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Host Cell
Extrinsic Component Of Postsynaptic Specialization Membrane
Glutamatergic Synapse
Nucleus
Cytosol
Molecular Function
RNA Binding
Protein Binding
Nuclear Localization Sequence Binding
Histone Deacetylase Binding
Nuclear Import Signal Receptor Activity
Transcription Coactivator Activity
Protein Binding
Biological Process
Regulation Of DNA Recombination
DNA Metabolic Process
NLS-bearing Protein Import Into Nucleus
Modulation By Virus Of Host Cellular Process
Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin
Postsynapse To Nucleus Signaling Pathway
Positive Regulation Of Viral Life Cycle
Transcription, DNA-templated
Signal Transduction
Cytoplasmic Sequestering Of NF-kappaB
Positive Regulation Of Transcription, DNA-templated
Cellular Response To Lipopolysaccharide
Pathways
CaMK IV-mediated phosphorylation of CREB
ISG15 antiviral mechanism
NS1 Mediated Effects on Host Pathways
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
Sensing of DNA Double Strand Breaks
Estrogen-dependent gene expression
Activation of NF-kappaB in B cells
RIP-mediated NFkB activation via ZBP1
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Feeling lonely (
29500382
)
General risk tolerance (MTAG) (
30643258
)
Loneliness (
29970889
)
Loneliness (MTAG) (
29970889
)
Refractive error (
32231278
)
Regular attendance at a religious group (
29970889
)
Interacting Genes
109 interacting genes:
ACTN1
ACTN4
ANKIB1
AP2B1
APOBEC1
APP
ARL4A
ARL5A
BAG6
BRCA1
BTBD2
CASP2
CCDC107
CDA
CDC42
CDK5RAP3
CHD3
CHEK2
CORO1B
CREB3L3
CREBBP
CSE1L
CSNK1A1
CUL4B
DCPS
DCTN2
DDIT3
EP300
EPB41
FEZ2
FN1
FTH1
GART
GMCL1
GRB2
GTF2IRD1
H1-0
HAP1
HMG20A
HNRNPC
HOMER2
HOMEZ
HSPA4
IFT20
IMMT
INO80E
ITK
JUN
KLC4
KPNB1
KRT18
KRT40
KRT8
LAMB2
LEF1
LZTS2
MAGED1
MAGEH1
MDFI
MLH1
MORC3
MORF4L1
MVP
NECAB2
NFKBIB
NMNAT1
NR3C1
NUP153
NUP50
NUP62
NUTM1
PAX5
PLAG1
PNMA5
PRKD3
PTMA
RAG1
RAN
RANBP2
RBM48
RBPMS
RECQL
RELA
RELB
RGL2
RILP
RNMT
SART3
SERTAD3
SGK1
SLC2A2
SPRY1
SRPK1
SUMO2
TADA2A
TAF3
TAF8
TANK
TBPL2
TP53
TRAF1
TRIM54
TSC22D4
TXNIP
UBR5
USHBP1
ZBTB7B
ZC3H12A
ZNF131
43 interacting genes:
APP
BAK1
BTBD6
BTRC
CDC25A
CHUK
CSNK2A1
CUL1
DNAJA3
ESR2
FHL3
GIT2
IKBKB
IKBKG
KPNA2
LRPPRC
MCC
MTIF2
NCOR2
NDUFB7
NFKB1
NFKB2
NFKBIA
NGFR
NKIRAS1
NKIRAS2
PDCD2
POLR1A
POLR1B
POLR1C
POLR1D
POLR1E
POLR1G
POLR2H
POLR2L
PPARG
RASAL2
REL
RELA
RXRA
SKP1
TSPAN1
VPS52
Entrez ID
3838
4793
HPRD ID
02818
07260
Ensembl ID
ENSG00000182481
ENSG00000104825
Uniprot IDs
P52292
G5E9C2
Q15653
PDB IDs
1EFX
1QGK
1QGR
3FEX
3FEY
3WPT
4E4V
4WV6
5H43
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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