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KPNA2 and H1-0
Data Source:
HPRD
(in vitro)
KPNA2
H1-0
Description
karyopherin subunit alpha 2
H1.0 linker histone
Image
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Host Cell
Extrinsic Component Of Postsynaptic Specialization Membrane
Glutamatergic Synapse
Chromatin
Nucleosome
Euchromatin
Nucleus
Nucleoplasm
Golgi Apparatus
Actin Cytoskeleton
Nuclear Body
Transcription Repressor Complex
Molecular Function
RNA Binding
Protein Binding
Nuclear Localization Sequence Binding
Histone Deacetylase Binding
Nuclear Import Signal Receptor Activity
Minor Groove Of Adenine-thymine-rich DNA Binding
Double-stranded DNA Binding
RNA Binding
Protein Binding
Chromatin DNA Binding
Nucleosomal DNA Binding
Biological Process
Regulation Of DNA Recombination
DNA Metabolic Process
NLS-bearing Protein Import Into Nucleus
Modulation By Virus Of Host Cellular Process
Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin
Postsynapse To Nucleus Signaling Pathway
Positive Regulation Of Viral Life Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Apoptotic DNA Fragmentation
Nucleosome Assembly
Chromatin Silencing
Nucleosome Positioning
Chromosome Condensation
Negative Regulation Of Chromatin Silencing
Negative Regulation Of DNA Recombination
Positive Regulation Of Transcription Regulatory Region DNA Binding
Pathways
CaMK IV-mediated phosphorylation of CREB
ISG15 antiviral mechanism
NS1 Mediated Effects on Host Pathways
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
Sensing of DNA Double Strand Breaks
Estrogen-dependent gene expression
Apoptosis induced DNA fragmentation
Formation of Senescence-Associated Heterochromatin Foci (SAHF)
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Feeling lonely (
29500382
)
General risk tolerance (MTAG) (
30643258
)
Loneliness (
29970889
)
Loneliness (MTAG) (
29970889
)
Refractive error (
32231278
)
Regular attendance at a religious group (
29970889
)
Interacting Genes
109 interacting genes:
ACTN1
ACTN4
ANKIB1
AP2B1
APOBEC1
APP
ARL4A
ARL5A
BAG6
BRCA1
BTBD2
CASP2
CCDC107
CDA
CDC42
CDK5RAP3
CHD3
CHEK2
CORO1B
CREB3L3
CREBBP
CSE1L
CSNK1A1
CUL4B
DCPS
DCTN2
DDIT3
EP300
EPB41
FEZ2
FN1
FTH1
GART
GMCL1
GRB2
GTF2IRD1
H1-0
HAP1
HMG20A
HNRNPC
HOMER2
HOMEZ
HSPA4
IFT20
IMMT
INO80E
ITK
JUN
KLC4
KPNB1
KRT18
KRT40
KRT8
LAMB2
LEF1
LZTS2
MAGED1
MAGEH1
MDFI
MLH1
MORC3
MORF4L1
MVP
NECAB2
NFKBIB
NMNAT1
NR3C1
NUP153
NUP50
NUP62
NUTM1
PAX5
PLAG1
PNMA5
PRKD3
PTMA
RAG1
RAN
RANBP2
RBM48
RBPMS
RECQL
RELA
RELB
RGL2
RILP
RNMT
SART3
SERTAD3
SGK1
SLC2A2
SPRY1
SRPK1
SUMO2
TADA2A
TAF3
TAF8
TANK
TBPL2
TP53
TRAF1
TRIM54
TSC22D4
TXNIP
UBR5
USHBP1
ZBTB7B
ZC3H12A
ZNF131
21 interacting genes:
APP
CCNE1
CDK1
CDK2
CDK4
CDK5
FBXO7
GRB2
HPF1
IKBKG
IPO5
IPO7
KPNA2
KPNB1
NEDD4L
NOA1
PARP1
PARP2
PRKCB
RAD51B
XBP1
Entrez ID
3838
3005
HPRD ID
02818
00819
Ensembl ID
ENSG00000182481
ENSG00000189060
Uniprot IDs
P52292
P07305
PDB IDs
1EFX
1QGK
1QGR
3FEX
3FEY
3WPT
4E4V
4WV6
5H43
6HQ1
6LA8
6LA9
6N88
6N89
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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