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NFKBIB and BTBD6

  • Data Source:
  • BioGRID (two hybrid)

NFKBIB

BTBD6

Description NFKB inhibitor beta BTB domain containing 6
Image No pdb structure
GO Annotations Cellular Component
  • Nucleus
  • Cytosol
  • Cytosol
Molecular Function
  • Transcription Coactivator Activity
  • Protein Binding
Biological Process
  • Transcription, DNA-templated
  • Signal Transduction
  • Cytoplasmic Sequestering Of NF-kappaB
  • Positive Regulation Of Transcription, DNA-templated
  • Cellular Response To Lipopolysaccharide
  • Neurogenesis
  • Post-translational Protein Modification
Pathways
  • Activation of NF-kappaB in B cells
  • RIP-mediated NFkB activation via ZBP1
  • TAK1 activates NFkB by phosphorylation and activation of IKKs complex
  • TRAF6 mediated NF-kB activation
  • Neddylation
  • Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Interacting Genes 43 interacting genes: APP BAK1 BTBD6 BTRC CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NDUFB7 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1G POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52 8 interacting genes: BTBD3 CUL3 DAXX NFKBIB NME7 NTAQ1 PAXIP1 TCEA2
Entrez ID 4793 90135
HPRD ID 07260 12540
Ensembl ID ENSG00000104825 ENSG00000184887
Uniprot IDs G5E9C2 Q15653 A0A384NYR4 Q96KE9
PDB IDs 2VKP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?

© Madhavi K. Ganapathiraju 2012-2025