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KPNA2 and TXNIP
Data Source:
HPRD
(two hybrid, in vitro)
KPNA2
TXNIP
Description
karyopherin subunit alpha 2
thioredoxin interacting protein
Image
GO Annotations
Cellular Component
Golgi Membrane
Nucleus
Nucleoplasm
Cytoplasm
Endoplasmic Reticulum Membrane
Cytosol
Membrane
Host Cell
Extrinsic Component Of Postsynaptic Specialization Membrane
Glutamatergic Synapse
Nucleus
Cytoplasm
Mitochondrial Intermembrane Space
Cytosol
Molecular Function
RNA Binding
Protein Binding
Nuclear Localization Sequence Binding
Histone Deacetylase Binding
Nuclear Import Signal Receptor Activity
Enzyme Inhibitor Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
Regulation Of DNA Recombination
DNA Metabolic Process
NLS-bearing Protein Import Into Nucleus
Modulation By Virus Of Host Cellular Process
Entry Of Viral Genome Into Host Nucleus Through Nuclear Pore Complex Via Importin
Postsynapse To Nucleus Signaling Pathway
Positive Regulation Of Viral Life Cycle
Negative Regulation Of Transcription By RNA Polymerase II
Protein Import Into Nucleus
Cell Cycle
Response To Mechanical Stimulus
Response To Glucose
Protein Transport
Keratinocyte Differentiation
Response To Estradiol
Response To Progesterone
Regulation Of Cell Population Proliferation
Response To Drug
Response To Hydrogen Peroxide
Positive Regulation Of Apoptotic Process
Negative Regulation Of Catalytic Activity
Platelet-derived Growth Factor Receptor Signaling Pathway
Response To Calcium Ion
Negative Regulation Of Cell Division
Cellular Response To Tumor Cell
Pathways
CaMK IV-mediated phosphorylation of CREB
ISG15 antiviral mechanism
NS1 Mediated Effects on Host Pathways
CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde
Sensing of DNA Double Strand Breaks
Estrogen-dependent gene expression
The NLRP3 inflammasome
The NLRP3 inflammasome
Regulation of FOXO transcriptional activity by acetylation
Purinergic signaling in leishmaniasis infection
Purinergic signaling in leishmaniasis infection
Drugs
Diseases
GWAS
Brain morphology (MOSTest) (
32665545
)
Feeling lonely (
29500382
)
General risk tolerance (MTAG) (
30643258
)
Loneliness (
29970889
)
Loneliness (MTAG) (
29970889
)
Refractive error (
32231278
)
Regular attendance at a religious group (
29970889
)
Interacting Genes
109 interacting genes:
ACTN1
ACTN4
ANKIB1
AP2B1
APOBEC1
APP
ARL4A
ARL5A
BAG6
BRCA1
BTBD2
CASP2
CCDC107
CDA
CDC42
CDK5RAP3
CHD3
CHEK2
CORO1B
CREB3L3
CREBBP
CSE1L
CSNK1A1
CUL4B
DCPS
DCTN2
DDIT3
EP300
EPB41
FEZ2
FN1
FTH1
GART
GMCL1
GRB2
GTF2IRD1
H1-0
HAP1
HMG20A
HNRNPC
HOMER2
HOMEZ
HSPA4
IFT20
IMMT
INO80E
ITK
JUN
KLC4
KPNB1
KRT18
KRT40
KRT8
LAMB2
LEF1
LZTS2
MAGED1
MAGEH1
MDFI
MLH1
MORC3
MORF4L1
MVP
NECAB2
NFKBIB
NMNAT1
NR3C1
NUP153
NUP50
NUP62
NUTM1
PAX5
PLAG1
PNMA5
PRKD3
PTMA
RAG1
RAN
RANBP2
RBM48
RBPMS
RECQL
RELA
RELB
RGL2
RILP
RNMT
SART3
SERTAD3
SGK1
SLC2A2
SPRY1
SRPK1
SUMO2
TADA2A
TAF3
TAF8
TANK
TBPL2
TP53
TRAF1
TRIM54
TSC22D4
TXNIP
UBR5
USHBP1
ZBTB7B
ZC3H12A
ZNF131
20 interacting genes:
DDIT4
ECD
FHL1
HDAC1
HDAC3
HSPB2
ITCH
KPNA2
MAPK1
NLGN3
PRKAA1
PTPN11
SCEL
SMURF2
TRAF6
TXN
TXNRD1
UBR5
ZBTB16
ZBTB32
Entrez ID
3838
10628
HPRD ID
02818
05964
Ensembl ID
ENSG00000182481
ENSG00000265972
Uniprot IDs
P52292
Q9H3M7
PDB IDs
1EFX
1QGK
1QGR
3FEX
3FEY
3WPT
4E4V
4WV6
5H43
4GEI
4GEJ
4GFX
4LL1
4LL4
4ROF
4ROJ
5CQ2
5DF6
5DWS
5DZD
Enriched GO Terms of Interacting Partners
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Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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