NFKBIB and NDUFB7

Data Source:
BioGRID (two hybrid)

		NFKBIB	NDUFB7
Description		NFKB inhibitor beta	NADH:ubiquinone oxidoreductase subunit B7
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Complex I Mitochondrial Intermembrane Space
	Molecular Function	Transcription Coactivator Activity Protein Binding	Protein Binding NADH Dehydrogenase (ubiquinone) Activity
	Biological Process	Transcription, DNA-templated Signal Transduction Cytoplasmic Sequestering Of NF-kappaB Positive Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide	Mitochondrial Electron Transport, NADH To Ubiquinone Mitochondrial Respiratory Chain Complex I Assembly
Pathways		Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation	Respiratory electron transport Complex I biogenesis
Drugs			NADH
Diseases
GWAS
Interacting Genes		43 interacting genes: APP BAK1 BTBD6 BTRC CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NDUFB7 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1G POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52	41 interacting genes: AGBL2 ANKRD36B ATG9A C1orf109 CAPN1 CCDC24 CCNC CDCA7L CDKN2D CHIC2 CINP CKAP4 CTNNA3 ENKD1 FAM161B FAM90A1 GEM GPATCH2L GYS1 KRTAP10-10 LMO2 MAGOHB MAK MEIS2 MKRN3 MLKL NDUFB2 NFKBIB NFKBID RCOR3 RECK RIPPLY1 RIPPLY2 SCNM1 SPRED2 STRA6 TLE5 ZNF330 ZNF417 ZNF564 ZNF587
Entrez ID		4793	4713
HPRD ID		07260	11957
Ensembl ID		ENSG00000104825	ENSG00000099795
Uniprot IDs		G5E9C2 Q15653	P17568
PDB IDs			5XTC 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?
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