NFKBIB and PDCD2

Data Source:
HPRD (in vitro)

		NFKBIB	PDCD2
Description		NFKB inhibitor beta	programmed cell death 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol	Nucleus Cytoplasm Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding	DNA Binding Protein Binding Enzyme Binding Metal Ion Binding
	Biological Process	Transcription, DNA-templated Signal Transduction Cytoplasmic Sequestering Of NF-kappaB Positive Regulation Of Transcription, DNA-templated Cellular Response To Lipopolysaccharide	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Apoptotic Process Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways		Activation of NF-kappaB in B cells RIP-mediated NFkB activation via ZBP1 TAK1 activates NFkB by phosphorylation and activation of IKKs complex TRAF6 mediated NF-kB activation
Drugs
Diseases
GWAS			Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653)
Interacting Genes		43 interacting genes: APP BAK1 BTBD6 BTRC CDC25A CHUK CSNK2A1 CUL1 DNAJA3 ESR2 FHL3 GIT2 IKBKB IKBKG KPNA2 LRPPRC MCC MTIF2 NCOR2 NDUFB7 NFKB1 NFKB2 NFKBIA NGFR NKIRAS1 NKIRAS2 PDCD2 POLR1A POLR1B POLR1C POLR1D POLR1E POLR1G POLR2H POLR2L PPARG RASAL2 REL RELA RXRA SKP1 TSPAN1 VPS52	7 interacting genes: ERRFI1 HCFC1 LSM8 NCOR1 NFKBIB PRKN TBC1D21
Entrez ID		4793	5134
HPRD ID		07260	02922
Ensembl ID		ENSG00000104825	ENSG00000071994
Uniprot IDs		G5E9C2 Q15653	A0A087WYJ3 Q16342
PDB IDs
Enriched GO Terms of Interacting Partners?
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