MESD and MRM1

Data Source:
BioGRID (two hybrid)

		MESD	MRM1
Description		mesoderm development LRP chaperone	mitochondrial rRNA methyltransferase 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Mitochondrion Mitochondrial Matrix
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding	RNA Binding Protein Binding RRNA (guanosine-2'-O-)-methyltransferase Activity
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	RRNA 2'-O-methylation
Pathways			rRNA modification in the mitochondrion
Drugs
Diseases
GWAS			Body mass index ( 26426971) Carotid intima media thickness x smoking interaction ( 32117412)
Interacting Genes		75 interacting genes: ABCG8 ABITRAM ACBD7 ADAL AKIRIN2 AKNAD1 AKT1 APP ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CCDC105 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FAM172A FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MCM9 MELTF MKNK2 MRM1 MTNR1A NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SIK1B SMARCB1 SNX5 SNX7 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	43 interacting genes: ADIPOQ AGTRAP AQP1 AQP2 AQP3 BRICD5 CCL4 CCL4L2 CDC42 CGGBP1 CMTM3 CMTM5 CNIH1 COQ8A DNAJC30 EEF1A1 ERG28 ESRRG FKBP7 ITGAM KLRG1 LPAR3 MAL2 MESD MGST3 NRM NXPE3 RHBDD2 RNASE10 SELENOK SPX STATH STX7 SYP SYT3 TMEM11 TMEM243 TMEM42 TMEM97 TRARG1 TTPA VKORC1L1 VSTM1
Entrez ID		23184	79922
HPRD ID		12129	08656
Ensembl ID		ENSG00000117899	ENSG00000278619
Uniprot IDs		Q14696	Q6IN84
PDB IDs
Enriched GO Terms of Interacting Partners?
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