MESD and TPM2

Data Source:
BioGRID (two hybrid)

		MESD	TPM2
Description		mesoderm development LRP chaperone	tropomyosin 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane	Cytosol Muscle Thin Filament Tropomyosin Actin Filament Actin Cytoskeleton
	Molecular Function	Molecular_function Protein Binding Identical Protein Binding Low-density Lipoprotein Particle Receptor Binding	Actin Binding Structural Constituent Of Muscle Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Actin Filament Binding
	Biological Process	Ossification Protein Folding Phagocytosis Mesoderm Development Wnt Signaling Pathway Protein Localization To Cell Surface Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering	Muscle Contraction Actin Filament Organization Muscle Filament Sliding Regulation Of ATPase Activity
Pathways			Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases			Cap myopathy Distal arthrogryposis (DA) Nemaline myopathy
GWAS			Immature fraction of reticulocytes ( 32888494) Platelet count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		75 interacting genes: ABCG8 ABITRAM ACBD7 ADAL AKIRIN2 AKNAD1 AKT1 APP ASH2L ATP6V1E1 ATP6V1E2 BORCS8 BORCS8-MEF2B BRD4 C17orf75 CCDC105 CDR2L CENATAC CENPH CHCHD1 CLP1 CNOT9 COL10A1 COL1A2 COX14 COX5A CUTC CYP4F11 DDX6 ENKD1 FAM13C FAM172A FARS2 FCER1A GEM GOLGA7 GPKOW GTPBP3 H2AB2 H2AB3 HSBP1L1 IGF1 KPNB1 LCE1A LRP5 LY96 MAGEB4 MAP1LC3B MCM9 MELTF MKNK2 MRM1 MTNR1A NRDE2 PMF1 PSMA5 QARS1 RCOR3 RFC3 SIK1B SMARCB1 SNX5 SNX7 TEX12 TEX48 TPM2 TREX2 TRMT2A TTC21A TTC23 TYMP UBQLN1 ZNF493 ZNF827 ZNF844	22 interacting genes: ABI2 ACTA1 ACTB FARS2 GRK2 JUN MAST2 MESD MRFAP1 NEB PDLIM7 PIK3CG RRAD S100A2 S100A4 SKIL SNAPIN TFPT TPM1 ZNF229 ZNF620 ZNF785
Entrez ID		23184	7169
HPRD ID		12129	11768
Ensembl ID		ENSG00000117899	ENSG00000198467
Uniprot IDs		Q14696	A7XZE4 P07951 Q5TCU3 V9HW25
PDB IDs
Enriched GO Terms of Interacting Partners?
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